CD19550

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD19550

CD19550

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Tnni3

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• troponin I, cardiac 3

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• troponin I, cardiac 3
• troponin I, cardiac muscle

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Tn1
• cTnI
• cardiac troponin I

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/21954

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• troponin I, cardiac 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:98783

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009406

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000035458

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.27674

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=191044

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Sonya C. Bardswell, et.al., Distinct sarcomeric substrates are responsible for protein kinase D-mediated regulation of cardiac myofilament Ca2+ sensitivity and cross-bridge cycling., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20018870
• Qun-Wei. Lu, et.al., Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20164197
• Bin. Wei, et.al., Mutual rescues between two dominant negative mutations in cardiac troponin I and cardiac troponin T., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20551314
• Yuejin. Li, et.al., Correcting diastolic dysfunction by Ca2+ desensitizing troponin in a transgenic mouse model of restrictive cardiomyopathy., Journal of molecular and cellular cardiology, 2010, 49
  http://rdf.ncbi.nlm.nih.gov/pubmed/20580639
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• I. Lyons, et.al., Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5., Genes & development, 1995, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/7628699
他4件を見る
• L. Zhu, et.al., Developmental regulation of troponin I isoform genes in striated muscles of transgenic mice., Developmental biology, 1995, 169
  http://rdf.ncbi.nlm.nih.gov/pubmed/7781893
• Z. Chen, et.al., Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice., Genes & development, 1994, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/7958896
• X. Guo, et.al., Mutagenesis of cardiac troponin I. Role of the unique NH2-terminal peptide in myofilament activation., The Journal of biological chemistry, 1994, 269
  http://rdf.ncbi.nlm.nih.gov/pubmed/8195157
• S. Ausoni, et.al., Structure and regulation of the mouse cardiac troponin I gene., The Journal of biological chemistry, 1994, 269
  http://rdf.ncbi.nlm.nih.gov/pubmed/8276817

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• vasculogenesis
  http://purl.obolibrary.org/obo/GO_0001570
• regulation of systemic arterial blood pressure by ischemic conditions
  http://purl.obolibrary.org/obo/GO_0001980
• actin binding
  http://purl.obolibrary.org/obo/GO_0003779
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• troponin complex
  http://purl.obolibrary.org/obo/GO_0005861
• cellular calcium ion homeostasis
  http://purl.obolibrary.org/obo/GO_0006874
他16件を見る
• regulation of muscle contraction
  http://purl.obolibrary.org/obo/GO_0006937
• regulation of smooth muscle contraction
  http://purl.obolibrary.org/obo/GO_0006940
• striated muscle contraction
  http://purl.obolibrary.org/obo/GO_0006941
• heart development
  http://purl.obolibrary.org/obo/GO_0007507
• calcium channel inhibitor activity
  http://purl.obolibrary.org/obo/GO_0019855
• protein kinase binding
  http://purl.obolibrary.org/obo/GO_0019901
• protein domain specific binding
  http://purl.obolibrary.org/obo/GO_0019904
• sarcomere
  http://purl.obolibrary.org/obo/GO_0030017
• troponin C binding
  http://purl.obolibrary.org/obo/GO_0030172
• troponin T binding
  http://purl.obolibrary.org/obo/GO_0031014
• negative regulation of ATPase activity
  http://purl.obolibrary.org/obo/GO_0032780
• contractile fiber
  http://purl.obolibrary.org/obo/GO_0043292
• calcium-dependent protein binding
  http://purl.obolibrary.org/obo/GO_0048306
• ventricular cardiac muscle tissue morphogenesis
  http://purl.obolibrary.org/obo/GO_0055010
• heart contraction
  http://purl.obolibrary.org/obo/GO_0060047
• cardiac muscle contraction
  http://purl.obolibrary.org/obo/GO_0060048

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04260
• http://www.genome.jp/dbget-bin/www_bget?map05410
• http://www.genome.jp/dbget-bin/www_bget?map05414

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Cardiac muscle contraction
• Dilated cardiomyopathy
• Hypertrophic cardiomyopathy (HCM)