CD20702

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD20702

CD20702

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Xrcc4

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• X-ray repair complementing defective repair in Chinese hamster cells 4

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• X-ray repair complementing defective repair in Chinese hamster cells 4
• DNA repair protein XRCC4
• X-ray repair cross-complementing protein 4

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AW413319
• 2310057B22Rik
• AW545101

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/108138

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• X-ray repair complementing defective repair in Chinese hamster cells 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1333799

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_028012

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000021615

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.37531

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=194363

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Radhika Pankaj. Kamdar, et.al., Radiation-induced XRCC4 association with chromatin DNA analyzed by biochemical fractionation., Journal of radiation research, 2010, 51
  http://rdf.ncbi.nlm.nih.gov/pubmed/20448413
• Y. Gao, et.al., A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis., Cell, 1998, 95
  http://rdf.ncbi.nlm.nih.gov/pubmed/9875844
• Francesca. Rucci, et.al., Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20133615
• Z. Li, et.al., The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination., Cell, 1995, 83
  http://rdf.ncbi.nlm.nih.gov/pubmed/8548796
• Cristian. Boboila, et.al., Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4., The Journal of experimental medicine, 2010, 207
  http://rdf.ncbi.nlm.nih.gov/pubmed/20142431
• Cristian. Boboila, et.al., Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20133803
• http://rdf.ncbi.nlm.nih.gov/pubmed/9889105
• Jennifer. Eccleston, et.al., Mismatch repair proteins MSH2, MLH1, and EXO1 are important for class-switch recombination events occurring in B cells that lack nonhomologous end joining., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21242524
• M. Yamano, et.al., Distribution of corticotropin-releasing factor and calcitonin gene-related peptide in the developing mouse cerebellum., Neuroscience research, 1994, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/8090368
• K M. Frank, et.al., Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV., Nature, 1998, 396
  http://rdf.ncbi.nlm.nih.gov/pubmed/9823897

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of fibroblast proliferation
  http://purl.obolibrary.org/obo/GO_0048146
• negative regulation of neuron apoptotic process
  http://purl.obolibrary.org/obo/GO_0043524
• immunoglobulin V(D)J recombination
  http://purl.obolibrary.org/obo/GO_0033152
• positive regulation of neurogenesis
  http://purl.obolibrary.org/obo/GO_0050769
• nonhomologous end joining complex
  http://purl.obolibrary.org/obo/GO_0070419
• immunoglobulin heavy chain V-D-J recombination
  http://purl.obolibrary.org/obo/GO_0071707
• DNA ligase IV complex
  http://purl.obolibrary.org/obo/GO_0032807
• double-strand break repair via nonhomologous end joining
  http://purl.obolibrary.org/obo/GO_0006303
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• DNA ligation involved in DNA repair
  http://purl.obolibrary.org/obo/GO_0051103
• T cell differentiation in thymus
  http://purl.obolibrary.org/obo/GO_0033077
• double-strand break repair
  http://purl.obolibrary.org/obo/GO_0006302
• isotype switching
  http://purl.obolibrary.org/obo/GO_0045190
• immunoglobulin light chain V-J recombination
  http://purl.obolibrary.org/obo/GO_0071708
• in utero embryonic development
  http://purl.obolibrary.org/obo/GO_0001701
• DNA ligation
  http://purl.obolibrary.org/obo/GO_0006266
• response to gamma radiation
  http://purl.obolibrary.org/obo/GO_0010332
• DNA repair
  http://purl.obolibrary.org/obo/GO_0006281
• response to ionizing radiation
  http://purl.obolibrary.org/obo/GO_0010212
• cellular response to DNA damage stimulus
  http://purl.obolibrary.org/obo/GO_0006974
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• DNA recombination
  http://purl.obolibrary.org/obo/GO_0006310
• central nervous system development
  http://purl.obolibrary.org/obo/GO_0007417
• response to X-ray
  http://purl.obolibrary.org/obo/GO_0010165
• pro-B cell differentiation
  http://purl.obolibrary.org/obo/GO_0002328
• V(D)J recombination
  http://purl.obolibrary.org/obo/GO_0033151
• positive regulation of ligase activity
  http://purl.obolibrary.org/obo/GO_0051351
• protein C-terminus binding
  http://purl.obolibrary.org/obo/GO_0008022
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• DNA-dependent protein kinase-DNA ligase 4 complex
  http://purl.obolibrary.org/obo/GO_0005958

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName