CD20950

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD20950

CD20950

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Mylip

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• myosin regulatory light chain interacting protein

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• myosin regulatory light chain-interacting protein
• inducible degrader of the LDL-receptor
• idol
• E3 ubiquitin-protein ligase MYLIP
• myosin regulatory light chain interacting protein

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Idol
• Mir
• 9430057C20Rik

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/218203

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• myosin regulatory light chain interacting protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388271

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_181043
• https://www.ncbi.nlm.nih.gov/nuccore/NM_153789

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000038175

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.212855
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.481228

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=610082

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Minako. Ishibashi, et.al., Reduced VLDL clearance in Apoe(-/-)Npc1(-/-) mice is associated with increased Pcsk9 and Idol expression and decreased hepatic LDL-receptor levels., Journal of lipid research, 2010, 51
  http://rdf.ncbi.nlm.nih.gov/pubmed/20562239
• Noam. Zelcer, et.al., LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor., Science (New York, N.Y.), 2009, 325
  http://rdf.ncbi.nlm.nih.gov/pubmed/19520913
• Cynthia. Hong, et.al., The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20427281
• Michelle N. Knowlton, et.al., The zebrafish band 4.1 member Mir is involved in cell movements associated with gastrulation., Developmental biology, 2003, 264
  http://rdf.ncbi.nlm.nih.gov/pubmed/14651927

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• ligase activity
  http://purl.obolibrary.org/obo/GO_0016874
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• positive regulation of protein catabolic process
  http://purl.obolibrary.org/obo/GO_0045732
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• cellular response to low-density lipoprotein particle stimulus
  http://purl.obolibrary.org/obo/GO_0071404
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• protein destabilization
  http://purl.obolibrary.org/obo/GO_0031648
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• movement of cell or subcellular component
  http://purl.obolibrary.org/obo/GO_0006928
• binding
  http://purl.obolibrary.org/obo/GO_0005488
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• nervous system development
  http://purl.obolibrary.org/obo/GO_0007399
• protein ubiquitination
  http://purl.obolibrary.org/obo/GO_0016567
• extrinsic component of membrane
  http://purl.obolibrary.org/obo/GO_0019898
• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856
• cytoskeletal protein binding
  http://purl.obolibrary.org/obo/GO_0008092
• ubiquitin-dependent protein catabolic process
  http://purl.obolibrary.org/obo/GO_0006511
• cholesterol homeostasis
  http://purl.obolibrary.org/obo/GO_0042632
• regulation of low-density lipoprotein particle receptor catabolic process
  http://purl.obolibrary.org/obo/GO_0032803
• negative regulation of low-density lipoprotein particle clearance
  http://purl.obolibrary.org/obo/GO_0010989

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName