CD21047

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD21047

CD21047

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Oas1b

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• 2'-5' oligoadenylate synthetase 1B

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• 2'-5'-oligoadenylate synthase 1B
• 2'-5'-oligoadenylate synthetase-like protein 1
• 2-5A synthetase 1B
• 2'-5'-oligoadenylate synthase-like protein 1
• (2-5')oligo(A) synthetase 1b
• 2'-5' oligoadenylate synthetase 1B
• (2-5')oligo(A) synthase 1B
• 2-5A synthase 1B
• 2',5'-oligoadenylate synthetase-like 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Oias2
• Oias-2
• Wnv
• Oas1
• Flavivirus resistance
• L1
• Flv
• Mmu-L1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/23961

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• 2'-5' oligoadenylate synthetase 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:97430

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001083925

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000029605

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.233471

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Kanako. Moritoh, et.al., Generation of congenic mouse strains by introducing the virus-resistant genes, Mx1 and Oas1b, of feral mouse-derived inbred strain MSM/Ms into the common strain C57BL/6J., The Japanese journal of veterinary research, 2009, 57
  http://rdf.ncbi.nlm.nih.gov/pubmed/19827744
• H. Elbahesh, et.al., The Flvr-encoded murine oligoadenylate synthetase 1b (Oas1b) suppresses 2-5A synthesis in intact cells., Virology, 2011, 409
  http://rdf.ncbi.nlm.nih.gov/pubmed/21056894
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• S K. Ghosh, et.al., Cloning, sequencing, and expression of two murine 2'-5'-oligoadenylate synthetases. Structure-function relationships., The Journal of biological chemistry, 1991, 266
  http://rdf.ncbi.nlm.nih.gov/pubmed/1651324
• M B. Darnell, et.al., Genetically determined resistance to infection with group B arboviruses. I. Distribution of the resistance gene among various mouse populations and characteristics of gene expression in vivo., The Journal of infectious diseases, 1974, 129
  http://rdf.ncbi.nlm.nih.gov/pubmed/4816304
• M N. Rutherford, et.al., The murine 2-5A synthetase locus: three distinct transcripts from two linked genes., Nucleic acids research, 1991, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/1709495
• http://rdf.ncbi.nlm.nih.gov/pubmed/16589143
• B. Cohen, et.al., Enhancer-like interferon responsive sequences of the human and murine (2'-5') oligoadenylate synthetase gene promoters., The EMBO journal, 1988, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/2457496
• Svetlana V. Scherbik, et.al., Knock-in of the Oas1b(r) allele into a flavivirus-induced disease susceptible mouse generates the resistant phenotype., Virology, 2007, 368
  http://rdf.ncbi.nlm.nih.gov/pubmed/17904183
• P N. Bhatt, et.al., Genetic resistance to lethal flavivrus encephalitis. II. Effect of immunosuppression., The Journal of infectious diseases, 1976, 134
  http://rdf.ncbi.nlm.nih.gov/pubmed/787445

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• response to virus
  http://purl.obolibrary.org/obo/GO_0009615

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05164
• http://www.genome.jp/dbget-bin/www_bget?map05162
• http://www.genome.jp/dbget-bin/www_bget?map05168
• http://www.genome.jp/dbget-bin/www_bget?map05160

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Hepatitis C
• Herpes simplex infection
• Measles
• Influenza A