CD21478

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD21478

CD21478

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ddb2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• damage specific DNA binding protein 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• DNA damage-binding protein 2
• damage specific DNA binding protein 2
• damage-specific DNA-binding protein 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 2610043A19Rik
• p48

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/107986

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• damage specific DNA binding protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1355314

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_028119

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000002109

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.389334

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=600811

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Thomas. Tan, et.al., p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice., Molecular and cellular biology, 2002, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/11971958
• Shigetoshi. Yokoyama, et.al., A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58., Developmental cell, 2009, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/20059953
• Tanya. Stoyanova, et.al., The xeroderma pigmentosum group E gene product DDB2 activates nucleotide excision repair by regulating the level of p21Waf1/Cip1., Molecular and cellular biology, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/17967871
• Tanya. Stoyanova, et.al., DDB2 decides cell fate following DNA damage., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19541625
• Toshiki. Itoh, et.al., DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/14769931
• Alex. Pines, et.al., Differential activity of UV-DDB in mouse keratinocytes and fibroblasts: impact on DNA repair and UV-induced skin cancer., DNA repair, 2009, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/18996499
• Taewon. Yoon, et.al., Tumor-prone phenotype of the DDB2-deficient mice., Oncogene, 2005, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/15558025
• F. Zolezzi, et.al., Studies of the murine DDB1 and DDB2 genes., Gene, 2000, 245
  http://rdf.ncbi.nlm.nih.gov/pubmed/10713455
• Sergey. Alekseev, et.al., Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation., Cancer research, 2005, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/16288018
• Nilotpal. Roy, et.al., DDB2, an essential mediator of premature senescence., Molecular and cellular biology, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20351176

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• pyrimidine dimer repair
  http://purl.obolibrary.org/obo/GO_0006290
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• cellular response to DNA damage stimulus
  http://purl.obolibrary.org/obo/GO_0006974
• response to UV
  http://purl.obolibrary.org/obo/GO_0009411
• protein autoubiquitination
  http://purl.obolibrary.org/obo/GO_0051865
• DNA repair
  http://purl.obolibrary.org/obo/GO_0006281
• macromolecular complex
  http://purl.obolibrary.org/obo/GO_0032991
• protein polyubiquitination
  http://purl.obolibrary.org/obo/GO_0000209

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04115
• http://www.genome.jp/dbget-bin/www_bget?map03420
• http://www.genome.jp/dbget-bin/www_bget?map04120

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Ubiquitin mediated proteolysis
• Nucleotide excision repair
• p53 signaling pathway