CD21594

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD21594

CD21594

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Prlr

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• prolactin receptor

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• prolactin receptor related sequence 1
• prolactin receptor
• PRL-R

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AI987712
• Pr-1
• Prlr-rs1
• Pr-3

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/19116

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• prolactin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:97763

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011169
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001253782
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001253781

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000005268

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.10516
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.442446

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=176761

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Rosemary S E. Brown, et.al., Distribution of prolactin-responsive neurons in the mouse forebrain., The Journal of comparative neurology, 2010, 518
  http://rdf.ncbi.nlm.nih.gov/pubmed/19882722
• J A. Davis, et.al., Expression of multiple forms of the prolactin receptor in mouse liver., Molecular endocrinology (Baltimore, Md.), 1989, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/2725531
• J A. Davis, et.al., Mutational analysis of mouse placental lactogen II, and molecular characterization of the mouse prolactin receptor., Progress in clinical and biological research, 1990, 342
  http://rdf.ncbi.nlm.nih.gov/pubmed/2381944
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Gloria K. Mak, et.al., Paternal recognition of adult offspring mediated by newly generated CNS neurons., Nature neuroscience, 2010, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/20453850
• A C. Herington, et.al., Hepatic binding of human and bovine growth hormones and ovine prolactin in the dwarf "little" mouse., Endocrinology, 1983, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/6303755
• R R. Gala, Influence of thyroxine and thyroxine with growth hormone and prolactin on splenocyte subsets and on the expression of interleukin-2 and prolactin receptors on splenocyte subsets of Snell dwarf mice., Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1995, 210
  http://rdf.ncbi.nlm.nih.gov/pubmed/7568281
• Chi-Bun. Chan, et.al., PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland development., The EMBO journal, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20075866
• Jason. Lanier, et.al., Brn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglion., Developmental dynamics : an official publication of the American Association of Anatomists, 2009, 238
  http://rdf.ncbi.nlm.nih.gov/pubmed/19877281
• C S. Barker, et.al., Activation of the prolactin receptor gene by promoter insertion in a Moloney murine leukemia virus-induced rat thymoma., Journal of virology, 1992, 66
  http://rdf.ncbi.nlm.nih.gov/pubmed/1404614

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• peptide hormone binding
  http://purl.obolibrary.org/obo/GO_0017046
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• activation of transmembrane receptor protein tyrosine kinase activity
  http://purl.obolibrary.org/obo/GO_0007171
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• JAK-STAT cascade
  http://purl.obolibrary.org/obo/GO_0007259
• protein kinase binding
  http://purl.obolibrary.org/obo/GO_0019901
• lactation
  http://purl.obolibrary.org/obo/GO_0007595
• mammary gland epithelial cell differentiation
  http://purl.obolibrary.org/obo/GO_0060644
• mammary gland alveolus development
  http://purl.obolibrary.org/obo/GO_0060749
• cytokine receptor activity
  http://purl.obolibrary.org/obo/GO_0004896
• mammary gland epithelium development
  http://purl.obolibrary.org/obo/GO_0061180
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• regulation of cell adhesion
  http://purl.obolibrary.org/obo/GO_0030155
• prolactin receptor activity
  http://purl.obolibrary.org/obo/GO_0004925
• regulation of epithelial cell differentiation
  http://purl.obolibrary.org/obo/GO_0030856
• prostate gland growth
  http://purl.obolibrary.org/obo/GO_0060736
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• cytokine-mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0019221
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04060
• http://www.genome.jp/dbget-bin/www_bget?map04630
• http://www.genome.jp/dbget-bin/www_bget?map04080

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Cytokine-cytokine receptor interaction
• Neuroactive ligand-receptor interaction
• Jak-STAT signaling pathway