CD21678

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD21678

CD21678

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Mcpt4

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• mast cell protease 4

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• serosal mast cell protease
• MSMCP
• mast cell protease 4

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Mcp4
• Mcp-4
• MMCP-4
• MMCP-4B
• MMCP-4A
• myonase

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/17227

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• mast cell protease 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:96940

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010779

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000061068

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.439684

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• M F. Gurish, et.al., Differential expression of secretory granule proteases in mouse mast cells exposed to interleukin 3 and c-kit ligand., The Journal of experimental medicine, 1992, 175
  http://rdf.ncbi.nlm.nih.gov/pubmed/1372640
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• George. Younan, et.al., The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/21076070
• Ida. Waern, et.al., Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation., Journal of immunology (Baltimore, Md. : 1950), 2009, 183
  http://rdf.ncbi.nlm.nih.gov/pubmed/19841188
• Lisa. Scandiuzzi, et.al., Mouse mast cell protease-4 deteriorates renal function by contributing to inflammation and fibrosis in immune complex-mediated glomerulonephritis., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20530261
• D S. Reynolds, et.al., Cloning of the cDNA and gene of mouse mast cell protease-6. Transcription by progenitor mast cells and mast cells of the connective tissue subclass., The Journal of biological chemistry, 1991, 266
  http://rdf.ncbi.nlm.nih.gov/pubmed/1995638
• W E. Serafin, et.al., Cloning of the cDNA and gene for mouse mast cell protease 4. Demonstration of its late transcription in mast cell subclasses and analysis of its homology to subclass-specific neutral proteases of the mouse and rat., The Journal of biological chemistry, 1991, 266
  http://rdf.ncbi.nlm.nih.gov/pubmed/1988455
• W E. Serafin, et.al., Identification and molecular cloning of a novel mouse mucosal mast cell serine protease., The Journal of biological chemistry, 1990, 265
  http://rdf.ncbi.nlm.nih.gov/pubmed/1688433
• R Y. Huang, et.al., Cloning and structural analysis of MMCP-1, MMCP-4 and MMCP-5, three mouse mast cell-specific serine proteases., European journal of immunology, 1991, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/2060576
• Katherine R. Groschwitz, et.al., Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/20018751

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• heparin binding
  http://purl.obolibrary.org/obo/GO_0008201
• peptide binding
  http://purl.obolibrary.org/obo/GO_0042277
• proteolysis
  http://purl.obolibrary.org/obo/GO_0006508
• serine-type endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0004252
• catalytic activity
  http://purl.obolibrary.org/obo/GO_0003824
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• serine-type peptidase activity
  http://purl.obolibrary.org/obo/GO_0008236
• peptidase activity
  http://purl.obolibrary.org/obo/GO_0008233
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName