CD21738

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD21738

CD21738

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Kng1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• kininogen 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• kininogen-1
• kininogen 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Kng
• L-kininogen
• H-kininigen

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16644

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• kininogen 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097705

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001102412
• https://www.ncbi.nlm.nih.gov/nuccore/NM_023125
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001102411

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022875

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.2160

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=612358

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• A. Ylönen, et.al., Atlantic salmon (Salmo salar L.) skin contains a novel kininogen and another cysteine proteinase inhibitor., European journal of biochemistry, 1999, 266
  http://rdf.ncbi.nlm.nih.gov/pubmed/10583403
• Masayasu. Kawasaki, et.al., Effect of His-Gly-Lys motif derived from domain 5 of high molecular weight kininogen on suppression of cancer metastasis both in vitro and in vivo., The Journal of biological chemistry, 2003, 278
  http://rdf.ncbi.nlm.nih.gov/pubmed/14506238
• Duncan J. Campbell, et.al., Genetic models provide unique insight into angiotensin and bradykinin peptides in the extravascular compartment of the heart in vivo., Clinical and experimental pharmacology & physiology, 2009, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/19673938
• J. Caubín, et.al., Isolation of genomic DNA fragments corresponding to genes modulated in vivo by a transcription factor., Nucleic acids research, 1994, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/7937138
• Oliver K. Bernhard, et.al., Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides., Journal of proteome research, 2007, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/17330941
• Masaoki. Takano, et.al., Lipopolysaccharide activates the kallikrein-kinin system in mouse choroid plexus cell line ECPC4., Neuroscience letters, 2008, 434
  http://rdf.ncbi.nlm.nih.gov/pubmed/18329172
• M. Takano, et.al., Molecular cloning of cDNAs for mouse low-molecular-weight and high-molecular-weight prekininogens., Biochimica et biophysica acta, 1997, 1352
  http://rdf.ncbi.nlm.nih.gov/pubmed/9199253
• Lene. Udby, et.al., Human CRISP-3 binds serum alpha(1)B-glycoprotein across species., Biochimica et biophysica acta, 2010, 1800
  http://rdf.ncbi.nlm.nih.gov/pubmed/20116414
• T. Chavakis, et.al., Haemostatic factors occupy new territory: the role of the urokinase receptor system and kininogen in inflammation., Biochemical Society transactions, 2002, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/12023845
• Sergei. Merkulov, et.al., Deletion of murine kininogen gene 1 (mKng1) causes loss of plasma kininogen and delays thrombosis., Blood, 2008, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/18000168

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• negative regulation of lymphocyte proliferation
  http://purl.obolibrary.org/obo/GO_0050672
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• negative regulation of T cell proliferation
  http://purl.obolibrary.org/obo/GO_0042130
• negative regulation of blood coagulation
  http://purl.obolibrary.org/obo/GO_0030195
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• receptor binding
  http://purl.obolibrary.org/obo/GO_0005102
• negative regulation of MAP kinase activity
  http://purl.obolibrary.org/obo/GO_0043407
• cysteine-type endopeptidase inhibitor activity
  http://purl.obolibrary.org/obo/GO_0004869
• perikaryon
  http://purl.obolibrary.org/obo/GO_0043204
• inflammatory response
  http://purl.obolibrary.org/obo/GO_0006954
• blood coagulation
  http://purl.obolibrary.org/obo/GO_0007596
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• negative regulation of proteolysis
  http://purl.obolibrary.org/obo/GO_0045861
• negative regulation of endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0010951
• protease binding
  http://purl.obolibrary.org/obo/GO_0002020
• regulation of endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0052548
• positive regulation of endothelial cell proliferation
  http://purl.obolibrary.org/obo/GO_0001938
• regulation of blood vessel size
  http://purl.obolibrary.org/obo/GO_0050880
• vasodilation
  http://purl.obolibrary.org/obo/GO_0042311
• negative regulation of cell adhesion
  http://purl.obolibrary.org/obo/GO_0007162
• peptidase inhibitor activity
  http://purl.obolibrary.org/obo/GO_0030414
• microsome
  http://purl.obolibrary.org/obo/GO_0005792
• positive regulation of MAPK cascade
  http://purl.obolibrary.org/obo/GO_0043410
• positive regulation of fibroblast proliferation
  http://purl.obolibrary.org/obo/GO_0048146
• negative regulation of peptidase activity
  http://purl.obolibrary.org/obo/GO_0010466
• positive regulation of cytosolic calcium ion concentration
  http://purl.obolibrary.org/obo/GO_0007204

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04610

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Complement and coagulation cascades