CD22097

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD22097

CD22097

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Sord

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• sorbitol dehydrogenase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• sorbitol dehydrogenase 1
• L-iditol 2-dehydrogenase
• sorbitol dehydrogenase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Sdh-1
• Sdh1
• Sodh-1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/20322

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• sorbitol dehydrogenase
  http://metadb.riken.jp/db/mgi_rdf/MGI:98266

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_146126

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000027227

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.432169
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.371580

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=182500

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Kevork. Hagopian, et.al., Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver., Biogerontology, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/18953666
• Miguel A. Lanaspa, et.al., ZAC1 is up-regulated by hypertonicity and decreases sorbitol dehydrogenase expression, allowing accumulation of sorbitol in kidney cells., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19423711
• R S. Holmes, et.al., Genetic variation, cellular distribution and ontogeny of sorbitol dehydrogenase and alcohol dehydrogenase isozymes in male reproductive tissues of the mouse., The Journal of experimental zoology, 1978, 206
  http://rdf.ncbi.nlm.nih.gov/pubmed/722274
• Alvin K H. Cheung, et.al., Gene deletion and pharmacological inhibition of aldose reductase protect against retinal ischemic injury., Experimental eye research, 2007, 85
  http://rdf.ncbi.nlm.nih.gov/pubmed/17727843
• R S. Holmes, et.al., Sorbitol dehydrogenase genetics in the mouse: a 'null' mutant in a 'European' C57BL strain., Animal blood groups and biochemical genetics, 1982, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/7171128
• M. Yasue, et.al., Chromosomal assignments of 23 biochemical loci of the rat by using rat x mouse somatic cell hybrids., Cytogenetics and cell genetics, 1991, 57
  http://rdf.ncbi.nlm.nih.gov/pubmed/1914521
• H. Satoh, et.al., Gene mapping in the Chinese hamster and conservation of syntenic groups and Q-band homologies between Chinese hamster and mouse chromosomes., Cytogenetics and cell genetics, 1985, 39
  http://rdf.ncbi.nlm.nih.gov/pubmed/3863747
• Wenlei. Cao, et.al., Sorbitol can fuel mouse sperm motility and protein tyrosine phosphorylation via sorbitol dehydrogenase., Biology of reproduction, 2009, 80
  http://rdf.ncbi.nlm.nih.gov/pubmed/18799757
• Alfred W H. Chan, et.al., Synergistic effect of osmotic and oxidative stress in slow-developing cataract formation., Experimental eye research, 2008, 87
  http://rdf.ncbi.nlm.nih.gov/pubmed/18760274
• S J. Andrews, et.al., Linkage analyses and biochemical genetics of sorbitol dehydrogenase-1 (Sdh-1) in the mouse., Biochemical genetics, 1983, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/6626150

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• identical protein binding
  http://purl.obolibrary.org/obo/GO_0042802
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• response to cadmium ion
  http://purl.obolibrary.org/obo/GO_0046686
• oxidation-reduction process
  http://purl.obolibrary.org/obo/GO_0055114
• cell projection
  http://purl.obolibrary.org/obo/GO_0042995
• flagellum
  http://purl.obolibrary.org/obo/GO_0019861
• NAD binding
  http://purl.obolibrary.org/obo/GO_0051287
• cilium
  http://purl.obolibrary.org/obo/GO_0005929
• sorbitol catabolic process
  http://purl.obolibrary.org/obo/GO_0006062
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• http://purl.obolibrary.org/obo/GO_0097722
• response to copper ion
  http://purl.obolibrary.org/obo/GO_0046688
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• L-xylitol catabolic process
  http://purl.obolibrary.org/obo/GO_0051160
• L-xylitol metabolic process
  http://purl.obolibrary.org/obo/GO_0051164
• fructose biosynthetic process
  http://purl.obolibrary.org/obo/GO_0046370
• NAD+ binding
  http://purl.obolibrary.org/obo/GO_0070403
• oxidoreductase activity
  http://purl.obolibrary.org/obo/GO_0016491
• L-iditol 2-dehydrogenase activity
  http://purl.obolibrary.org/obo/GO_0003939
• sorbitol metabolic process
  http://purl.obolibrary.org/obo/GO_0006060
• sperm motility
  http://purl.obolibrary.org/obo/GO_0030317
• response to hormone
  http://purl.obolibrary.org/obo/GO_0009725

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00051
• http://www.genome.jp/dbget-bin/www_bget?map01100

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Metabolic pathways
• Fructose and mannose metabolism