CD22151

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD22151

CD22151

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Lrpap1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• low density lipoprotein receptor-related protein associated protein 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• low density lipoprotein receptor related protein, associated protein 1
• low density lipoprotein receptor-related protein associated protein 1
• Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) (Heparin binding protein-44) (HBP-44)
• heparin-binding protein 44
• HBP-44
• alpha-2-MRAP
• alpha-2-macroglobulin receptor-associated protein
• low density lipoprotein receptor-related protein-associated protein 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• RAP
• AI790446
• C77774
• AA617339
• HBP44
• AU042172

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16976

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• low density lipoprotein receptor-related protein associated protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96829

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_013587

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000029103

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.277661

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=104225

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• K. Lorent, et.al., Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein., Neuroscience, 1995, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/7542371
• T. Furukawa, et.al., A heparin binding protein whose expression increases during differentiation of embryonal carcinoma cells to parietal endoderm cells: cDNA cloning and sequence analysis., Journal of biochemistry, 1990, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/2229028
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• L. Umans, et.al., Targeted inactivation of the mouse alpha 2-macroglobulin gene., The Journal of biological chemistry, 1995, 270
  http://rdf.ncbi.nlm.nih.gov/pubmed/7544347
• Guilian. Xu, et.al., Receptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice., PloS one, 2008, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/18776935
• Takahisa. Kanekiyo, et.al., Receptor-associated protein interacts with amyloid-beta peptide and promotes its cellular uptake., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19826010
• S. Lisi, et.al., Kidney abnormalities in low density lipoprotein receptor associated protein knockout mice., Journal of endocrinological investigation, 2008, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/18296906
• F. Van Leuven, et.al., Molecular analysis of the human and mouse alpha 2M family., Annals of the New York Academy of Sciences, 1994, 737
  http://rdf.ncbi.nlm.nih.gov/pubmed/7524394
• François. Gerbe, et.al., Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst., Developmental biology, 2008, 313
  http://rdf.ncbi.nlm.nih.gov/pubmed/18083160
• T E. Willnow, et.al., Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo., Proceedings of the National Academy of Sciences of the United States of America, 1995, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/7538675

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• very-low-density lipoprotein particle receptor binding
  http://purl.obolibrary.org/obo/GO_0070326
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• heparin binding
  http://purl.obolibrary.org/obo/GO_0008201
• negative regulation of signal transduction
  http://purl.obolibrary.org/obo/GO_0009968
• receptor antagonist activity
  http://purl.obolibrary.org/obo/GO_0048019
• negative regulation of protein binding
  http://purl.obolibrary.org/obo/GO_0032091
• lipase binding
  http://purl.obolibrary.org/obo/GO_0035473
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• rough endoplasmic reticulum lumen
  http://purl.obolibrary.org/obo/GO_0048237
• negative regulation of receptor activity
  http://purl.obolibrary.org/obo/GO_2000272
• negative regulation of very-low-density lipoprotein particle clearance
  http://purl.obolibrary.org/obo/GO_0010916
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• vesicle
  http://purl.obolibrary.org/obo/GO_0031982
• low-density lipoprotein particle receptor binding
  http://purl.obolibrary.org/obo/GO_0050750
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName