CD22373

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD22373

CD22373

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Wwp1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• WW domain containing E3 ubiquitin protein ligase 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• WW domain containing E3 ubiquitin protein ligase 1
• WW domain-containing protein 1
• NEDD4-like E3 ubiquitin-protein ligase WWP1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Tiul1
• AIP5
• SDRP1
• 8030445B08Rik

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/107568

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• WW domain containing E3 ubiquitin protein ligase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861728

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_177327

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000041058

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.78312

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602307

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Y. Piao, et.al., Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method., Genome research, 2001, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/11544199
• K. Huang, et.al., A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis., Gene, 2000, 252
  http://rdf.ncbi.nlm.nih.gov/pubmed/10903445
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Y. Li, et.al., WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer., Oncogene, 2009, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/19561640
• Roland H. Friedel, et.al., EUCOMM--the European conditional mouse mutagenesis program., Briefings in functional genomics & proteomics, 2007, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/17967808
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• Shu-Mang. Feng, et.al., The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation., Molecular and cellular biology, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19047365
• M D. Conkright, et.al., Lung Krüppel-like factor contains an autoinhibitory domain that regulates its transcriptional activation by binding WWP1, an E3 ubiquitin ligase., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11375995
• Shigetoshi. Yokoyama, et.al., A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58., Developmental cell, 2009, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/20059953

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• protein ubiquitination
  http://purl.obolibrary.org/obo/GO_0016567
• T cell differentiation
  http://purl.obolibrary.org/obo/GO_0030217
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• cellular protein modification process
  http://purl.obolibrary.org/obo/GO_0006464
• lung development
  http://purl.obolibrary.org/obo/GO_0030324
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• ligase activity
  http://purl.obolibrary.org/obo/GO_0016874
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• proteasome-mediated ubiquitin-dependent protein catabolic process
  http://purl.obolibrary.org/obo/GO_0043161
• protein modification process
  http://purl.obolibrary.org/obo/GO_0036211
• negative regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045892
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• ubiquitin-dependent protein catabolic process
  http://purl.obolibrary.org/obo/GO_0006511
• acid-amino acid ligase activity
  http://purl.obolibrary.org/obo/GO_0016881

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04144
• http://www.genome.jp/dbget-bin/www_bget?map04120

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Ubiquitin mediated proteolysis
• Endocytosis