CD22923

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD22923

CD22923

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Slco1b2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• solute carrier organic anion transporter family, member 1b2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• solute carrier family 21 member 10
• liver-specific organic anion transporter 1
• solute carrier organic anion transporter family member 1B2
• solute carrier family (organic anion transporter) member 10
• solute carrier family 21 (organic anion transporter), member 10
• solute carrier organic anion transporter family, member 1b2
• solute carrier family 21 (organic anion transporter), member 6

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Slc21a6
• 7330442B20Rik
• OATP2
• lst-1
• mlst-1
• Oatp4
• OATP-C
• Slc21a10
• Oatp1b2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/28253

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• solute carrier organic anion transporter family, member 1b2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1351899

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_020495

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000030236

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.272223

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605495

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Xingguo. Cheng, et.al., Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers., Toxicological sciences : an official journal of the Society of Toxicology, 2008, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/18703564
• Hong. Lu, et.al., Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR., Toxicological sciences : an official journal of the Society of Toxicology, 2008, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/18296417
• Raymond. Evers, et.al., Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity., Molecular pharmacology, 2008, 74
  http://rdf.ncbi.nlm.nih.gov/pubmed/18492796
• Satoki. Imai, et.al., Analysis of DNA methylation and histone modification profiles of liver-specific transporters., Molecular pharmacology, 2009, 75
  http://rdf.ncbi.nlm.nih.gov/pubmed/19047482
• Iván L. Csanaky, et.al., Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice., Hepatology (Baltimore, Md.), 2011, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/20949553
• K. Ogura, et.al., Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1)., Biochemical and biophysical research communications, 2000, 272
  http://rdf.ncbi.nlm.nih.gov/pubmed/10833452
• Jack. Phan, et.al., The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/11682476
• Jaeick. Lee, et.al., Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS., Molecular & cellular proteomics : MCP, 2007, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/17208939
• Evita. van de Steeg, et.al., Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20644253
• http://rdf.ncbi.nlm.nih.gov/pubmed/19400585

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• transport
  http://purl.obolibrary.org/obo/GO_0006810
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• drug transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0015238
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• bile acid transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0015125
• oligopeptide transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0035673
• ion transport
  http://purl.obolibrary.org/obo/GO_0006811
• drug transport
  http://purl.obolibrary.org/obo/GO_0015893
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• oligopeptide transport
  http://purl.obolibrary.org/obo/GO_0006857
• bile acid and bile salt transport
  http://purl.obolibrary.org/obo/GO_0015721
• drug transmembrane transport
  http://purl.obolibrary.org/obo/GO_0006855
• basolateral plasma membrane
  http://purl.obolibrary.org/obo/GO_0016323
• transporter activity
  http://purl.obolibrary.org/obo/GO_0005215
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• integral component of plasma membrane
  http://purl.obolibrary.org/obo/GO_0005887
• organic anion transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0008514

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04976

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Bile secretion