CD23108

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD23108

CD23108

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Klra1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• killer cell lectin-like receptor, subfamily A, member 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• ly-49a
• t lymphocyte antigen A1
• T-cell surface glycoprotein YE1/48
• natural killer cell receptor Ly49A
• class I MHC receptor KLRA22
• lymphocyte antigen 49a
• killer cell lectin-like receptor, subfamily A, member 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Ly49o<129>
• Ly49A
• Klra22
• Ly49v
• Ly49a
• A1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16627

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• killer cell lectin-like receptor, subfamily A, member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:101907

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_016659

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000079853

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.333431
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.24399

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Sungjune. Kim, et.al., Impact of bacteria on the phenotype, functions, and therapeutic activities of invariant NKT cells in mice., The Journal of clinical investigation, 2008, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/18451996
• H C. Morse, Genetic nomenclature for loci controlling surface antigens of mouse hemopoietic cells., Journal of immunology (Baltimore, Md. : 1950), 1992, 149
  http://rdf.ncbi.nlm.nih.gov/pubmed/1431091
• W M. Yokoyama, et.al., Chromosomal location of the Ly-49 (A1, YE1/48) multigene family. Genetic association with the NK 1.1 antigen., Journal of immunology (Baltimore, Md. : 1950), 1990, 145
  http://rdf.ncbi.nlm.nih.gov/pubmed/1975828
• Mark T. Orr, et.al., Natural killer cells in NOD.NK1.1 mice acquire cytolytic function during viral infection and provide protection against cytomegalovirus., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20733071
• Jianmei W. Leavenworth, et.al., Engagement of transgenic Ly49A inhibits mouse CD4 cell activation by disrupting T cell receptor, but not CD28, signaling., Cellular immunology, 2009, 257
  http://rdf.ncbi.nlm.nih.gov/pubmed/19362713
• S. Wong, et.al., Ly-49 multigene family. New members of a superfamily of type II membrane proteins with lectin-like domains., Journal of immunology (Baltimore, Md. : 1950), 1991, 147
  http://rdf.ncbi.nlm.nih.gov/pubmed/1869832
• W M. Yokoyama, et.al., cDNA cloning of mouse NKR-P1 and genetic linkage with LY-49. Identification of a natural killer cell gene complex on mouse chromosome 6., Journal of immunology (Baltimore, Md. : 1950), 1991, 147
  http://rdf.ncbi.nlm.nih.gov/pubmed/1680927
• Daisuke. Ito, et.al., Essential role of the Ly49A stalk region for immunological synapse formation and signaling., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19549850
• Anick. Chalifour, et.al., A Role for cis Interaction between the Inhibitory Ly49A receptor and MHC class I for natural killer cell education., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19249231
• A A. Scalzo, et.al., The effect of the Cmv-1 resistance gene, which is linked to the natural killer cell gene complex, is mediated by natural killer cells., Journal of immunology (Baltimore, Md. : 1950), 1992, 149
  http://rdf.ncbi.nlm.nih.gov/pubmed/1378069

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• external side of plasma membrane
  http://purl.obolibrary.org/obo/GO_0009897
• signal transducer activity
  http://purl.obolibrary.org/obo/GO_0004871
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05332
• http://www.genome.jp/dbget-bin/www_bget?map04650

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Natural killer cell mediated cytotoxicity
• Graft-versus-host disease