CD24104

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD24104

CD24104

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Adora3

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• adenosine A3 receptor

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• adenosine receptor A3
• adenosine A3 receptor
• G-protein coupled receptor 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• A3AR
• AA3R
• Gpcr 2
• Gpcr2
• 4930578J19Rik
• 1700001D09Rik
• A3R
• ARA3

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/11542

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• adenosine A3 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104847

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009631
• https://www.ncbi.nlm.nih.gov/nuccore/NM_027025
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001174169

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000000562;%20ENSMUSG00000074344

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.235024

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=600445

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• T M. Wilkie, et.al., Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors., Genomics, 1993, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/8288218
• D. Leshem-Lev, et.al., Adenosine A(1) and A (3) receptor agonists reduce hypoxic injury through the involvement of P38 MAPK., Molecular and cellular biochemistry, 2010, 345
  http://rdf.ncbi.nlm.nih.gov/pubmed/20730620
• R. Allikmets, et.al., A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy., Nature genetics, 1997, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/9054934
• Lindsey A. Burnett, et.al., Testicular expression of Adora3i2 in Adora3 knockout mice reveals a role of mouse A3Ri2 and human A3Ri3 adenosine receptors in sperm., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20732875
• V. Ramkumar, et.al., The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells., The Journal of biological chemistry, 1993, 268
  http://rdf.ncbi.nlm.nih.gov/pubmed/8349579
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Yujin. Zhang, et.al., Detrimental effects of adenosine signaling in sickle cell disease., Nature medicine, 2011, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/21170046
• Z. Zhao, et.al., Characterization of the mouse A3 adenosine receptor gene: exon/intron organization and promoter activity., Genomics, 1999, 57
  http://rdf.ncbi.nlm.nih.gov/pubmed/10191095
• Z. Zhao, et.al., Chromosomal mapping of the mouse A3 adenosine receptor gene, Adora3., Genomics, 1995, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/8595892
• Mattias. Enoksson, et.al., Mast cells as sensors of cell injury through IL-33 recognition., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21239713

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• regulation of norepinephrine secretion
  http://purl.obolibrary.org/obo/GO_0014061
• G-protein coupled receptor activity
  http://purl.obolibrary.org/obo/GO_0004930
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• positive regulation of mast cell degranulation
  http://purl.obolibrary.org/obo/GO_0043306
• positive regulation of mucus secretion
  http://purl.obolibrary.org/obo/GO_0070257
• positive regulation of inflammatory response
  http://purl.obolibrary.org/obo/GO_0050729
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• positive regulation of phosphatidylinositol 3-kinase signaling
  http://purl.obolibrary.org/obo/GO_0014068
• G-protein coupled receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007186
• integral component of plasma membrane
  http://purl.obolibrary.org/obo/GO_0005887
• G-protein coupled adenosine receptor activity
  http://purl.obolibrary.org/obo/GO_0001609
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• positive regulation of leukocyte migration
  http://purl.obolibrary.org/obo/GO_0002687
• adenosine receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0001973
• histamine secretion by mast cell
  http://purl.obolibrary.org/obo/GO_0002553
• presynaptic membrane
  http://purl.obolibrary.org/obo/GO_0042734
• positive regulation of calcium-mediated signaling
  http://purl.obolibrary.org/obo/GO_0050850
• signal transducer activity
  http://purl.obolibrary.org/obo/GO_0004871

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04080

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Neuroactive ligand-receptor interaction