CD26070

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD26070

CD26070

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pde3a

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• phosphodiesterase 3A, cGMP inhibited

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• cGMP-inhibited phosphodiesterase
• cGMP-inhibited 3',5'-cyclic phosphodiesterase A
• phosphodiesterase 3A, cGMP inhibited
• cyclic GMP-inhibited phosphodiesterase A
• CGI-PDE A

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• A930022O17Rik
• C87899

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/54611

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• phosphodiesterase 3A, cGMP inhibited
  http://metadb.riken.jp/db/mgi_rdf/MGI:1860764

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_018779

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000041741

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.103728

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=123805

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Bing. Sun, et.al., Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice., Cellular signalling, 2007, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/17482796
• Kenji. Omori, et.al., Overview of PDEs and their regulation., Circulation research, 2007, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/17307970
• Silvia. Masciarelli, et.al., Cyclic nucleotide phosphodiesterase 3A-deficient mice as a model of female infertility., The Journal of clinical investigation, 2004, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/15254586
• Sergio. Vaccari, et.al., Generation of mouse oocytes defective in cAMP synthesis and degradation: endogenous cyclic AMP is essential for meiotic arrest., Developmental biology, 2008, 316
  http://rdf.ncbi.nlm.nih.gov/pubmed/18280465
• Seung Jin. Han, et.al., Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation., The EMBO journal, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/17124499
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Jeong Su. Oh, et.al., Wee1B, Myt1, and Cdc25 function in distinct compartments of the mouse oocyte to control meiotic resumption., The Journal of cell biology, 2010, 188
  http://rdf.ncbi.nlm.nih.gov/pubmed/20083600
• K. Shitsukawa, et.al., Cloning and characterization of the cyclic guanosine monophosphate-inhibited phosphodiesterase PDE3A expressed in mouse oocyte., Biology of reproduction, 2001, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/11420239
• Sergio. Vaccari, et.al., Cyclic GMP signaling is involved in the luteinizing hormone-dependent meiotic maturation of mouse oocytes., Biology of reproduction, 2009, 81
  http://rdf.ncbi.nlm.nih.gov/pubmed/19474061
• Axel. Visel, et.al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo., Nucleic acids research, 2004, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/14681479

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• phosphoric diester hydrolase activity
  http://purl.obolibrary.org/obo/GO_0008081
• response to drug
  http://purl.obolibrary.org/obo/GO_0042493
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• cellular response to cGMP
  http://purl.obolibrary.org/obo/GO_0071321
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• oocyte maturation
  http://purl.obolibrary.org/obo/GO_0001556
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• cAMP catabolic process
  http://purl.obolibrary.org/obo/GO_0006198
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
  http://purl.obolibrary.org/obo/GO_0004119
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• cGMP-mediated signaling
  http://purl.obolibrary.org/obo/GO_0019934
• insoluble fraction
  http://purl.obolibrary.org/obo/GO_0005626
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• positive regulation of vascular permeability
  http://purl.obolibrary.org/obo/GO_0043117
• regulation of meiosis
  http://purl.obolibrary.org/obo/GO_0040020
• catalytic activity
  http://purl.obolibrary.org/obo/GO_0003824
• positive regulation of oocyte development
  http://purl.obolibrary.org/obo/GO_0060282
• negative regulation of vascular permeability
  http://purl.obolibrary.org/obo/GO_0043116
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• cAMP-mediated signaling
  http://purl.obolibrary.org/obo/GO_0019933
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cAMP binding
  http://purl.obolibrary.org/obo/GO_0030552

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04914
• http://www.genome.jp/dbget-bin/www_bget?map04910
• http://www.genome.jp/dbget-bin/www_bget?map00230

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Progesterone-mediated oocyte maturation
• Insulin signaling pathway
• Purine metabolism