CD27652

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD27652

CD27652

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Lnpep

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• leucyl/cystinyl aminopeptidase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• OTase
• leucyl-cystinyl aminopeptidase
• oxytocinase
• cystinyl aminopeptidase
• leucyl/cystinyl aminopeptidase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• gp160
• CAP
• PLAP
• 2010309L07Rik
• IRAP
• 4732490P18Rik
• vp165

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/240028

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• leucyl/cystinyl aminopeptidase
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387123

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_172827

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000023845

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.393452
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.328807

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=151300

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Susanna R. Keller, The insulin-regulated aminopeptidase: a companion and regulator of GLUT4., Frontiers in bioscience : a journal and virtual library, 2003, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/12700100
• Yasushi. Numaguchi, et.al., Ablation of angiotensin IV receptor attenuates hypofibrinolysis via PAI-1 downregulation and reduces occlusive arterial thrombosis., Arteriosclerosis, thrombosis, and vascular biology, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19745198
• Yohko. Hirata, et.al., Vimentin binds IRAP and is involved in GLUT4 vesicle trafficking., Biochemical and biophysical research communications, 2011, 405
  http://rdf.ncbi.nlm.nih.gov/pubmed/21216232
• Ingrid. Jordens, et.al., Insulin-regulated aminopeptidase is a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to specialized insulin-regulated vesicles., Molecular biology of the cell, 2010, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/20410133
• H. Jiang, et.al., GLUT4 ablation in mice results in redistribution of IRAP to the plasma membrane., Biochemical and biophysical research communications, 2001, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/11394912
• Susanna R. Keller, et.al., Mice deficient in the insulin-regulated membrane aminopeptidase show substantial decreases in glucose transporter GLUT4 levels but maintain normal glucose homeostasis., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/11884418
• Eugenia. Carvalho, et.al., GLUT4 overexpression or deficiency in adipocytes of transgenic mice alters the composition of GLUT4 vesicles and the subcellular localization of GLUT4 and insulin-responsive aminopeptidase., The Journal of biological chemistry, 2004, 279
  http://rdf.ncbi.nlm.nih.gov/pubmed/14985357
• Anthony L. Albiston, et.al., Gene knockout of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory., Neurobiology of learning and memory, 2010, 93
  http://rdf.ncbi.nlm.nih.gov/pubmed/19660563
• Elodie. Segura, et.al., Different cross-presentation pathways in steady-state and inflammatory dendritic cells., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19918052
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• G-protein coupled receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007186
• proteolysis
  http://purl.obolibrary.org/obo/GO_0006508
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• peptide hormone binding
  http://purl.obolibrary.org/obo/GO_0017046
• angiotensin receptor activity
  http://purl.obolibrary.org/obo/GO_0001595
• regulation of long-term neuronal synaptic plasticity
  http://purl.obolibrary.org/obo/GO_0048169
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• neuropeptide catabolic process
  http://purl.obolibrary.org/obo/GO_0010813
• perinuclear region of cytoplasm
  http://purl.obolibrary.org/obo/GO_0048471
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• insulin-responsive compartment
  http://purl.obolibrary.org/obo/GO_0032593
• metallopeptidase activity
  http://purl.obolibrary.org/obo/GO_0008237
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• vesicle
  http://purl.obolibrary.org/obo/GO_0031982
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• microsome
  http://purl.obolibrary.org/obo/GO_0005792
• intracellular organelle
  http://purl.obolibrary.org/obo/GO_0043229
• peptide catabolic process
  http://purl.obolibrary.org/obo/GO_0043171
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• aminopeptidase activity
  http://purl.obolibrary.org/obo/GO_0004177
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• peptidase activity
  http://purl.obolibrary.org/obo/GO_0008233
• response to hormone
  http://purl.obolibrary.org/obo/GO_0009725
• neuronal cell body
  http://purl.obolibrary.org/obo/GO_0043025
• protein catabolic process
  http://purl.obolibrary.org/obo/GO_0030163

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04614

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Renin-angiotensin system