CD28053

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28053

CD28053

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Eif2a

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• eukaryotic translation initiation factor 2A

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• eIF-2A
• eukaryotic translation initiation factor 2A

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• D3Ertd194e
• D030048D22

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/229317

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• eukaryotic translation initiation factor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098684

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001005509

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000027810

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.21617

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=609234

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Donalyn. Scheuner, et.al., Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis., The Journal of biological chemistry, 2006, 281
  http://rdf.ncbi.nlm.nih.gov/pubmed/16717090
• Andrew M. Fribley, et.al., Proteasome inhibitor PS-341 induces apoptosis in cisplatin-resistant squamous cell carcinoma cells by induction of Noxa., The Journal of biological chemistry, 2006, 281
  http://rdf.ncbi.nlm.nih.gov/pubmed/16928686
• Andreas I. Papadakis, et.al., eIF2{alpha} Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1{alpha}., Cancer research, 2010, 70
  http://rdf.ncbi.nlm.nih.gov/pubmed/20924113
• Elena. Bevilacqua, et.al., eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20338999
• Masashi. Yamaji, et.al., Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3., Reproduction (Cambridge, England), 2010, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/19861488
• Osamu. Hori, et.al., Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress., Molecular and cellular biology, 2006, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/16705175
• Zeynep. Firtina, et.al., Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19858219
• Atsushi. Saito, et.al., Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2., The Journal of biological chemistry, 2011, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/21135100
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• T. Ito, et.al., Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase., Proceedings of the National Academy of Sciences of the United States of America, 1994, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/7519779

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• regulation of translation
  http://purl.obolibrary.org/obo/GO_0006417
• eukaryotic translation initiation factor 2 complex
  http://purl.obolibrary.org/obo/GO_0005850
• positive regulation of signal transduction
  http://purl.obolibrary.org/obo/GO_0009967
• translation
  http://purl.obolibrary.org/obo/GO_0006412
• tRNA binding
  http://purl.obolibrary.org/obo/GO_0000049
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• SREBP signaling pathway
  http://purl.obolibrary.org/obo/GO_0032933
• translation initiation factor activity
  http://purl.obolibrary.org/obo/GO_0003743
• translational initiation
  http://purl.obolibrary.org/obo/GO_0006413
• ribosome assembly
  http://purl.obolibrary.org/obo/GO_0042255
• ribosome binding
  http://purl.obolibrary.org/obo/GO_0043022

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName