CD28321

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28321

CD28321

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Rc3h1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• RING CCCH (C3H) domains 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• protein Sanroque
• RING finger and C3H zinc finger protein 1
• RING CCCH (C3H) domains 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• N28103
• 5730557L09Rik
• roquin
• mKIAA2025
• Gm551

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/381305

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• RING CCCH (C3H) domains 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2685397

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001024952

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000040423

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.329667

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=609424

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Di. Yu, et.al., Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA., Nature, 2007, 450
  http://rdf.ncbi.nlm.nih.gov/pubmed/18172933
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• Daniel E. Zak, et.al., Systems biology of innate immunity., Immunological reviews, 2009, 227
  http://rdf.ncbi.nlm.nih.gov/pubmed/19120490
• Michelle A. Linterman, et.al., Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19217324
• Charis E. Teh, et.al., T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20668237
• Carola G. Vinuesa, et.al., A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity., Nature, 2005, 435
  http://rdf.ncbi.nlm.nih.gov/pubmed/15917799
• Elke. Glasmacher, et.al., Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression., Nature immunology, 2010, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/20639877
• Michelle A. Linterman, et.al., Follicular helper T cells are required for systemic autoimmunity., The Journal of experimental medicine, 2009, 206
  http://rdf.ncbi.nlm.nih.gov/pubmed/19221396
• Noriko. Okazaki, et.al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries., DNA research : an international journal for rapid publication of reports on genes and genomes, 2004, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/15368895

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• posttranscriptional regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010608
• regulation of T cell receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0050856
• regulation of germinal center formation
  http://purl.obolibrary.org/obo/GO_0002634
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• cytoplasmic mRNA processing body
  http://purl.obolibrary.org/obo/GO_0000932
• negative regulation of T-helper cell differentiation
  http://purl.obolibrary.org/obo/GO_0045623
• negative regulation of B cell proliferation
  http://purl.obolibrary.org/obo/GO_0030889
• nuclear-transcribed mRNA catabolic process
  http://purl.obolibrary.org/obo/GO_0000956
• regulation of mRNA stability
  http://purl.obolibrary.org/obo/GO_0043488
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• negative regulation of germinal center formation
  http://purl.obolibrary.org/obo/GO_0002635
• nucleic acid binding
  http://purl.obolibrary.org/obo/GO_0003676
• cytoplasmic mRNA processing body assembly
  http://purl.obolibrary.org/obo/GO_0033962
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• negative regulation of activated T cell proliferation
  http://purl.obolibrary.org/obo/GO_0046007
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• cytoplasmic stress granule
  http://purl.obolibrary.org/obo/GO_0010494
• RNA binding
  http://purl.obolibrary.org/obo/GO_0003723

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName