CD29770

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD29770

CD29770

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Dvl1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• dishevelled, dsh homolog 1 (Drosophila)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• segment polarity protein dishevelled homolog DVL-1
• dishevelled-1
• dishevelled, dsh homolog 1 (Drosophila)
• DSH homolog 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• mKIAA4029
• Dvl

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/13542

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• dishevelled segment polarity protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:94941

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010091

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000029071

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.3400

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601365

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Yosuke. Funato, et.al., Nucleoredoxin sustains Wnt/β-catenin signaling by retaining a pool of inactive dishevelled protein., Current biology : CB, 2010, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/20970343
• Ho-Jin. Lee, et.al., Identification of transmembrane protein 88 (TMEM88) as a dishevelled-binding protein., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/21044957
• D J. Sussman, et.al., Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled., Developmental biology, 1994, 166
  http://rdf.ncbi.nlm.nih.gov/pubmed/7958461
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Takuji. Tsuji, et.al., Involvement of p114-RhoGEF and Lfc in Wnt-3a- and dishevelled-induced RhoA activation and neurite retraction in N1E-115 mouse neuroblastoma cells., Molecular biology of the cell, 2010, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/20810787
• P E. Neumann, et.al., Multifactorial inheritance of neural tube defects: localization of the major gene and recognition of modifiers in ct mutant mice., Nature genetics, 1994, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/8054974
• M L. Roller, et.al., Chromosomal localization of the zinc finger protein 15, Zfp15, on mouse chromosome 4., Mammalian genome : official journal of the International Mammalian Genome Society, 1995, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/7613041
• D R. Beier, et.al., Haplotype analysis of intra-specific backcross curly-tail mice confirms the localization of ct to chromosome 4., Mammalian genome : official journal of the International Mammalian Genome Society, 1995, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/7613032
• D R. Beier, et.al., Mapping genes in the mouse using single-strand conformation polymorphism analysis of recombinant inbred strains and interspecific crosses., Proceedings of the National Academy of Sciences of the United States of America, 1992, 89
  http://rdf.ncbi.nlm.nih.gov/pubmed/1409609
• Daniele V F. Tauriello, et.al., Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl., Molecular cell, 2010, 37
  http://rdf.ncbi.nlm.nih.gov/pubmed/20227366

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• microtubule cytoskeleton
  http://purl.obolibrary.org/obo/GO_0015630
• positive regulation of Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0030177
• cell
  http://purl.obolibrary.org/obo/GO_0005623
• prepulse inhibition
  http://purl.obolibrary.org/obo/GO_0060134
• signal transducer activity
  http://purl.obolibrary.org/obo/GO_0004871
• axon extension
  http://purl.obolibrary.org/obo/GO_0048675
• synapse
  http://purl.obolibrary.org/obo/GO_0045202
• neurotransmitter secretion
  http://purl.obolibrary.org/obo/GO_0007269
• microtubule
  http://purl.obolibrary.org/obo/GO_0005874
• canonical Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0060070
• frizzled binding
  http://purl.obolibrary.org/obo/GO_0005109
• social behavior
  http://purl.obolibrary.org/obo/GO_0035176
• convergent extension involved in neural plate elongation
  http://purl.obolibrary.org/obo/GO_0022007
• protein localization to microtubule
  http://purl.obolibrary.org/obo/GO_0035372
• protein kinase binding
  http://purl.obolibrary.org/obo/GO_0019901
• identical protein binding
  http://purl.obolibrary.org/obo/GO_0042802
• growth cone
  http://purl.obolibrary.org/obo/GO_0030426
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0016055
• intracellular signal transduction
  http://purl.obolibrary.org/obo/GO_0035556
• regulation of protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0001932
• cell cortex
  http://purl.obolibrary.org/obo/GO_0005938
• clathrin-coated vesicle
  http://purl.obolibrary.org/obo/GO_0030136
• synaptosome
  http://purl.obolibrary.org/obo/GO_0019717
• negative regulation of protein binding
  http://purl.obolibrary.org/obo/GO_0032091
• neuromuscular junction development
  http://purl.obolibrary.org/obo/GO_0007528
• Wnt signaling pathway, planar cell polarity pathway
  http://purl.obolibrary.org/obo/GO_0060071
• receptor clustering
  http://purl.obolibrary.org/obo/GO_0043113
• planar cell polarity pathway involved in neural tube closure
  http://purl.obolibrary.org/obo/GO_0090179
• dendrite morphogenesis
  http://purl.obolibrary.org/obo/GO_0048813
• neuronal cell body
  http://purl.obolibrary.org/obo/GO_0043025
• cochlea morphogenesis
  http://purl.obolibrary.org/obo/GO_0090103
• collateral sprouting
  http://purl.obolibrary.org/obo/GO_0048668
• skeletal muscle acetylcholine-gated channel clustering
  http://purl.obolibrary.org/obo/GO_0071340
• negative regulation of protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0001933
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0006366
• axon
  http://purl.obolibrary.org/obo/GO_0030424
• positive regulation of neuron projection development
  http://purl.obolibrary.org/obo/GO_0010976
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• axonogenesis
  http://purl.obolibrary.org/obo/GO_0007409
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• enzyme binding
  http://purl.obolibrary.org/obo/GO_0019899
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• synapse organization
  http://purl.obolibrary.org/obo/GO_0050808
• negative regulation of protein kinase activity
  http://purl.obolibrary.org/obo/GO_0006469
• regulation of neurotransmitter levels
  http://purl.obolibrary.org/obo/GO_0001505
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• protein localization to nucleus
  http://purl.obolibrary.org/obo/GO_0034504
• positive regulation of canonical Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0090263
• convergent extension involved in organogenesis
  http://purl.obolibrary.org/obo/GO_0060029
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• axon guidance
  http://purl.obolibrary.org/obo/GO_0007411
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• dendrite
  http://purl.obolibrary.org/obo/GO_0030425
• cytoplasmic microtubule organization
  http://purl.obolibrary.org/obo/GO_0031122
• Rac GTPase binding
  http://purl.obolibrary.org/obo/GO_0048365
• cytoplasmic vesicle
  http://purl.obolibrary.org/obo/GO_0031410

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05166
• http://www.genome.jp/dbget-bin/www_bget?map05217
• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map04310
• http://www.genome.jp/dbget-bin/www_bget?map04330
• http://www.genome.jp/dbget-bin/www_bget?map04916

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Wnt signaling pathway
• Melanogenesis
• HTLV-I infection
• Basal cell carcinoma
• Notch signaling pathway
• Pathways in cancer