CD30139

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD30139

CD30139

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Eef2k

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• eukaryotic elongation factor-2 kinase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
• eukaryotic elongation factor-2 kinase
• eukaroytic elongation factor 2 kinase
• eEF-2 kinase
• eukaryotic elongation factor 2 kinase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• C86191
• eEF-2K

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/13631

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• eukaryotic elongation factor-2 kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1195261

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/XM_003084730
• https://www.ncbi.nlm.nih.gov/nuccore/NM_007908
• https://www.ncbi.nlm.nih.gov/nuccore/XM_003086637
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001251826

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000035064;%20ENSMUSG00000073853

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.470116
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.25997
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.361795

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=606968

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Qin. Shen, et.al., Expression QTL and regulatory network analysis of microtubule-associated protein tau gene., Parkinsonism & related disorders, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19233709
• Heh-In. Im, et.al., Post-training dephosphorylation of eEF-2 promotes protein synthesis for memory consolidation., PloS one, 2009, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/19823585
• A G. Ryazanov, et.al., Alpha-kinases: a new class of protein kinases with a novel catalytic domain., Current biology : CB, 1999, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/10021370
• M. Boyce, et.al., A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death., Cell death and differentiation, 2008, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/18188169
• A G. Ryazanov, et.al., Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9144159
• Aslam A. Khan, et.al., Resveratrol regulates pathologic angiogenesis by a eukaryotic elongation factor-2 kinase-regulated pathway., The American journal of pathology, 2010, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/20472894
• M. Gschwendt, et.al., Elongation factor-2 kinase: effective inhibition by the novel protein kinase inhibitor rottlerin and relative insensitivity towards staurosporine., FEBS letters, 1994, 338
  http://rdf.ncbi.nlm.nih.gov/pubmed/8307162
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Hiroyuki. Sakagami, et.al., Transient up-regulation of elongation factor-2 kinase (Ca2+/calmodulin-dependent protein kinase III) messenger RNA in developing mouse brain., Neuroscience letters, 2002, 330
  http://rdf.ncbi.nlm.nih.gov/pubmed/12213630
• Bénédicte F. Py, et.al., A critical role of eEF-2K in mediating autophagy in response to multiple cellular stresses., Autophagy, 2009, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/19221463

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0004674
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• elongation factor-2 kinase activity
  http://purl.obolibrary.org/obo/GO_0004686
• translation factor activity, RNA binding
  http://purl.obolibrary.org/obo/GO_0008135
• calcium ion binding
  http://purl.obolibrary.org/obo/GO_0005509
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• regulation of protein autophosphorylation
  http://purl.obolibrary.org/obo/GO_0031952
• protein autophosphorylation
  http://purl.obolibrary.org/obo/GO_0046777
• binding
  http://purl.obolibrary.org/obo/GO_0005488
• translational elongation
  http://purl.obolibrary.org/obo/GO_0006414
• calmodulin binding
  http://purl.obolibrary.org/obo/GO_0005516

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName