CD30350

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD30350

CD30350

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Slc9a3r1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• solute carrier family 9 isoform A3 regulatory factor 1
• sodium-hydrogen exchanger regulatory factor 1
• EBP50
• Na(+)/H(+) exchange regulatory cofactor NHE-RF1
• regulatory cofactor of Na(+)/H(+) exchanger
• ezrin-radixin-moesin-binding phosphoprotein 50
• solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
• solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• EBP-50
• NHERF-1
• NHE-RF
• sodium-hydrogen exchanger regulatory factor
• NHERF1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/26941

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1349482

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_012030

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000020733

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.27842

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=604990

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• J. He, et.al., Phosphorylation and cell cycle-dependent regulation of Na+/H+ exchanger regulatory factor-1 by Cdc2 kinase., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11533036
• R A. Hall, et.al., The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange., Nature, 1998, 392
  http://rdf.ncbi.nlm.nih.gov/pubmed/9560162
• Edward J. Weinman, et.al., Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20571032
• E J. Weinman, et.al., Molecular cloning of the cDNA and promoter sequences for the mouse sodium-hydrogen exchanger regulatory factor., Biochimica et biophysica acta, 1999, 1447
  http://rdf.ncbi.nlm.nih.gov/pubmed/10500246
• Man. Li, et.al., NHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and function., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20404332
• Andrew P. Evan, et.al., Comparison of the pathology of interstitial plaque in human ICSF stone patients to NHERF-1 and THP-null mice., Urological research, 2010, 38
  http://rdf.ncbi.nlm.nih.gov/pubmed/21063698
• Katsuhiko. Itoh, et.al., Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly., Journal of immunology (Baltimore, Md. : 1950), 2002, 168
  http://rdf.ncbi.nlm.nih.gov/pubmed/11777944
• S M. Gisler, et.al., Interaction of the type IIa Na/Pi cotransporter with PDZ proteins., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11099500
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• M. Donowitz, et.al., Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesicles., Physiological genomics, 2010, 42A
  http://rdf.ncbi.nlm.nih.gov/pubmed/20736413

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cell projection
  http://purl.obolibrary.org/obo/GO_0042995
• cell periphery
  http://purl.obolibrary.org/obo/GO_0071944
• protein self-association
  http://purl.obolibrary.org/obo/GO_0043621
• glutathione transport
  http://purl.obolibrary.org/obo/GO_0034635
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• negative regulation of protein kinase B signaling
  http://purl.obolibrary.org/obo/GO_0051898
• renal absorption
  http://purl.obolibrary.org/obo/GO_0070293
• chloride channel regulator activity
  http://purl.obolibrary.org/obo/GO_0017081
• cellular protein localization
  http://purl.obolibrary.org/obo/GO_0034613
• negative regulation of platelet-derived growth factor receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0010642
• renal sodium ion transport
  http://purl.obolibrary.org/obo/GO_0003096
• receptor binding
  http://purl.obolibrary.org/obo/GO_0005102
• brush border membrane
  http://purl.obolibrary.org/obo/GO_0031526
• cellular phosphate ion homeostasis
  http://purl.obolibrary.org/obo/GO_0030643
• growth factor receptor binding
  http://purl.obolibrary.org/obo/GO_0070851
• actin cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0030036
• PDZ domain binding
  http://purl.obolibrary.org/obo/GO_0030165
• adenylate cyclase-activating dopamine receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007191
• regulation of protein kinase activity
  http://purl.obolibrary.org/obo/GO_0045859
• regulation of excretion
  http://purl.obolibrary.org/obo/GO_0044062
• negative regulation of phosphatidylinositol 3-kinase signaling
  http://purl.obolibrary.org/obo/GO_0014067
• cAMP-mediated signaling
  http://purl.obolibrary.org/obo/GO_0019933
• negative regulation of ERK1 and ERK2 cascade
  http://purl.obolibrary.org/obo/GO_0070373
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• phosphatase binding
  http://purl.obolibrary.org/obo/GO_0019902
• microvillus
  http://purl.obolibrary.org/obo/GO_0005902
• negative regulation of cell migration
  http://purl.obolibrary.org/obo/GO_0030336
• beta-2 adrenergic receptor binding
  http://purl.obolibrary.org/obo/GO_0031698
• negative regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008285
• negative regulation of sodium ion transport
  http://purl.obolibrary.org/obo/GO_0010766
• intracellular membrane-bounded organelle
  http://purl.obolibrary.org/obo/GO_0043231
• Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0016055
• apical part of cell
  http://purl.obolibrary.org/obo/GO_0045177
• negative regulation of cell motility
  http://purl.obolibrary.org/obo/GO_2000146
• cell cortex
  http://purl.obolibrary.org/obo/GO_0005938
• beta-catenin binding
  http://purl.obolibrary.org/obo/GO_0008013
• microvillus membrane
  http://purl.obolibrary.org/obo/GO_0031528
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• microvillus assembly
  http://purl.obolibrary.org/obo/GO_0030033
• apical plasma membrane
  http://purl.obolibrary.org/obo/GO_0016324
• negative regulation of sodium:proton antiporter activity
  http://purl.obolibrary.org/obo/GO_0032416
• phospholipase C-activating dopamine receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0060158
• dopamine receptor binding
  http://purl.obolibrary.org/obo/GO_0050780
• centrosome
  http://purl.obolibrary.org/obo/GO_0005813
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• bile acid secretion
  http://purl.obolibrary.org/obo/GO_0032782

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName