CD30781

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD30781

CD30781

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pklr

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• pyruvate kinase liver and red blood cell

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• pyruvate kinase liver and red blood cell
• L-PK
• pyruvate kinase isozymes R/L

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Pk-1
• Pk1
• R-PK

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18770

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• pyruvate kinase liver and red blood cell
  http://metadb.riken.jp/db/mgi_rdf/MGI:97604

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001099779
• https://www.ncbi.nlm.nih.gov/nuccore/NM_013631

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000041237

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.383180

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=609712

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Ken-ichi. Aisaki, et.al., Glycolytic inhibition by mutation of pyruvate kinase gene increases oxidative stress and causes apoptosis of a pyruvate kinase deficient cell line., Experimental hematology, 2007, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/17662887
• R J. Oakey, et.al., Chromosomal mapping of the high affinity Fc gamma receptor gene., Immunogenetics, 1992, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/1347284
• Murat. Cankaya, et.al., An analysis of expression patterns of genes encoding proteins with catalytic activities., BMC genomics, 2007, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/17626619
• L A. Fitton, et.al., The liver/erythrocyte pyruvate kinase gene complex [Pk-1] in the mouse: regulatory gene mutations., Genetical research, 1991, 58
  http://rdf.ncbi.nlm.nih.gov/pubmed/1802805
• A. Bessis, et.al., Chromosomal localization of the mouse genes coding for alpha 2, alpha 3, alpha 4 and beta 2 subunits of neuronal nicotinic acetylcholine receptor., FEBS letters, 1990, 264
  http://rdf.ncbi.nlm.nih.gov/pubmed/2338144
• T. Serikawa, et.al., Rat gene mapping using PCR-analyzed microsatellites., Genetics, 1992, 131
  http://rdf.ncbi.nlm.nih.gov/pubmed/1628813
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Hitoshi. Kanno, et.al., Transgenic rescue of hemolytic anemia due to red blood cell pyruvate kinase deficiency., Haematologica, 2007, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/17550844
• N A. Dower, et.al., Organization and chromosomal locations of Rap1a/Krev sequences in the mouse., Mammalian genome : official journal of the International Mammalian Genome Society, 1992, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/1617222
• Marie-France. Roy, et.al., Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in mice., The Journal of experimental medicine, 2007, 204
  http://rdf.ncbi.nlm.nih.gov/pubmed/17998386

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• response to ATP
  http://purl.obolibrary.org/obo/GO_0033198
• response to cAMP
  http://purl.obolibrary.org/obo/GO_0051591
• pyruvate biosynthetic process
  http://purl.obolibrary.org/obo/GO_0042866
• glycolytic process
  http://purl.obolibrary.org/obo/GO_0006096
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• response to heat
  http://purl.obolibrary.org/obo/GO_0009408
• pyruvate kinase activity
  http://purl.obolibrary.org/obo/GO_0004743
• cellular response to insulin stimulus
  http://purl.obolibrary.org/obo/GO_0032869
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• ATP biosynthetic process
  http://purl.obolibrary.org/obo/GO_0006754
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• response to other organism
  http://purl.obolibrary.org/obo/GO_0051707
• response to lithium ion
  http://purl.obolibrary.org/obo/GO_0010226
• carbohydrate metabolic process
  http://purl.obolibrary.org/obo/GO_0005975

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00010
• http://www.genome.jp/dbget-bin/www_bget?map04950
• http://www.genome.jp/dbget-bin/www_bget?map00620
• http://www.genome.jp/dbget-bin/www_bget?map04910
• http://www.genome.jp/dbget-bin/www_bget?map04930
• http://www.genome.jp/dbget-bin/www_bget?map00230
• http://www.genome.jp/dbget-bin/www_bget?map01100

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Maturity onset diabetes of the young
• Purine metabolism
• Metabolic pathways
• Glycolysis / Gluconeogenesis
• Type II diabetes mellitus
• Insulin signaling pathway
• Pyruvate metabolism