CD33316

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD33316

CD33316

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Rassf1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• Ras association (RalGDS/AF-6) domain family member 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• protein 123F2
• ras association domain-containing protein 1
• RASSF1A tumor suppressor
• Ras association (RalGDS/AF-6) domain family member 1
• Ras association (RalGDS/AF-6) domain family 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AA536941
• Rassf1A
• REH3P21
• NORE2A
• RDA32
• 123F2
• 123F protein
• AU044980
• Rassf1B
• Rassf1C

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/56289

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• Ras association (RalGDS/AF-6) domain family member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928386

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001243748
• https://www.ncbi.nlm.nih.gov/nuccore/NM_019713

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000010067

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.440982
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.12091

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605082

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Dominic P. Del Re, et.al., Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20890045
• Stella. Tommasi, et.al., RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1., Oncogene, 2002, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/11965544
• Jin. Sun, et.al., Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains., Carcinogenesis, 2011, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/21097531
• D G. Burbee, et.al., Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression., Journal of the National Cancer Institute, 2001, 93
  http://rdf.ncbi.nlm.nih.gov/pubmed/11333291
• M I. Lerman, et.al., The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium., Cancer research, 2000, 60
  http://rdf.ncbi.nlm.nih.gov/pubmed/11085536
• S. Tommasi, et.al., Loss of Rassf1a enhances p53-mediated tumor predisposition and accelerates progression to aneuploidy., Oncogene, 2011, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20890300
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Stella. Tommasi, et.al., Tumor susceptibility of Rassf1a knockout mice., Cancer research, 2005, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/15665283
• Delvac. Oceandy, et.al., Tumor suppressor Ras-association domain family 1 isoform A is a novel regulator of cardiac hypertrophy., Circulation, 2009, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/19652091
• L. van der Weyden, et.al., The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesis., Molecular and cellular biology, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16135822

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856
• microtubule cytoskeleton
  http://purl.obolibrary.org/obo/GO_0015630
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• cell cycle
  http://purl.obolibrary.org/obo/GO_0007049
• identical protein binding
  http://purl.obolibrary.org/obo/GO_0042802
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• protein stabilization
  http://purl.obolibrary.org/obo/GO_0050821
• negative regulation of cell cycle arrest
  http://purl.obolibrary.org/obo/GO_0071157
• positive regulation of protein ubiquitination
  http://purl.obolibrary.org/obo/GO_0031398
• Ras protein signal transduction
  http://purl.obolibrary.org/obo/GO_0007265
• intracellular signal transduction
  http://purl.obolibrary.org/obo/GO_0035556
• protein N-terminus binding
  http://purl.obolibrary.org/obo/GO_0047485
• cell cycle arrest
  http://purl.obolibrary.org/obo/GO_0007050
• cellular response to DNA damage stimulus
  http://purl.obolibrary.org/obo/GO_0006974
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• microtubule
  http://purl.obolibrary.org/obo/GO_0005874
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map05219
• http://www.genome.jp/dbget-bin/www_bget?map05223

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Non-small cell lung cancer
• Bladder cancer
• Pathways in cancer