CD33515

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD33515

CD33515

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Alox5

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• arachidonate 5-lipoxygenase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• 5-lipoxygenase
• arachidonate 5-lipoxygenase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 5LX
• F730011J02
• AI850497
• 5LO
• 5-LO
• 5-LOX

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/11689

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• arachidonate 5-lipoxygenase
  http://metadb.riken.jp/db/mgi_rdf/MGI:87999

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009662

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000025701

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.41072

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=152390

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• C D. Funk, et.al., Targeted gene disruption by homologous recombination. Toward an understanding of specific blood cell functions., Annals of the New York Academy of Sciences, 1994, 714
  http://rdf.ncbi.nlm.nih.gov/pubmed/8017775
• Mei. Chen, et.al., Joint tissues amplify inflammation and alter their invasive behavior via leukotriene B4 in experimental inflammatory arthritis., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20876351
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Tsutomu. Nagashima, et.al., Arachidonate 5-lipoxygenase establishes adaptive humoral immunity by controlling primary B cells and their cognate T-cell help., The American journal of pathology, 2011, 178
  http://rdf.ncbi.nlm.nih.gov/pubmed/21224059
• X S. Chen, et.al., cDNA cloning, expression, mutagenesis, intracellular localization, and gene chromosomal assignment of mouse 5-lipoxygenase., The Journal of biological chemistry, 1995, 270
  http://rdf.ncbi.nlm.nih.gov/pubmed/7629107
• X S. Chen, et.al., Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene., Nature, 1994, 372
  http://rdf.ncbi.nlm.nih.gov/pubmed/7969451
• J L. Goulet, et.al., Altered inflammatory responses in leukotriene-deficient mice., Proceedings of the National Academy of Sciences of the United States of America, 1994, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/7809134
• Eric C. Cheon, et.al., Mast cell 5-lipoxygenase activity promotes intestinal polyposis in APCDelta468 mice., Cancer research, 2011, 71
  http://rdf.ncbi.nlm.nih.gov/pubmed/21216893
• C D. Funk, et.al., Leukotriene-deficient mice generated by targeted disruption of the 5-lipoxygenase gene., Advances in prostaglandin, thromboxane, and leukotriene research, 1995, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/7732821
• Victoria A. Blaho, et.al., 5-Lipoxygenase-deficient mice infected with Borrelia burgdorferi develop persistent arthritis., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21270404

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• nuclear envelope
  http://purl.obolibrary.org/obo/GO_0005635
• leukotriene biosynthetic process
  http://purl.obolibrary.org/obo/GO_0019370
• nuclear membrane
  http://purl.obolibrary.org/obo/GO_0031965
• leukotriene metabolic process
  http://purl.obolibrary.org/obo/GO_0006691
• oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
  http://purl.obolibrary.org/obo/GO_0016702
• inflammatory response
  http://purl.obolibrary.org/obo/GO_0006954
• nuclear matrix
  http://purl.obolibrary.org/obo/GO_0016363
• sensory perception of pain
  http://purl.obolibrary.org/obo/GO_0019233
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• oxidoreductase activity
  http://purl.obolibrary.org/obo/GO_0016491
• positive regulation of vasoconstriction
  http://purl.obolibrary.org/obo/GO_0045907
• linoleate 13S-lipoxygenase activity
  http://purl.obolibrary.org/obo/GO_0016165
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• dendrite
  http://purl.obolibrary.org/obo/GO_0030425
• arachidonic acid metabolic process
  http://purl.obolibrary.org/obo/GO_0019369
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• acute inflammatory response
  http://purl.obolibrary.org/obo/GO_0002526
• nuclear envelope lumen
  http://purl.obolibrary.org/obo/GO_0005641
• leukotriene production involved in inflammatory response
  http://purl.obolibrary.org/obo/GO_0002540
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• lipoxygenase pathway
  http://purl.obolibrary.org/obo/GO_0019372
• arachidonate 5-lipoxygenase activity
  http://purl.obolibrary.org/obo/GO_0004051
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• oxidation-reduction process
  http://purl.obolibrary.org/obo/GO_0055114
• sarcolemma
  http://purl.obolibrary.org/obo/GO_0042383
• iron ion binding
  http://purl.obolibrary.org/obo/GO_0005506

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00590
• http://www.genome.jp/dbget-bin/www_bget?map01100
• http://www.genome.jp/dbget-bin/www_bget?map05145

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Metabolic pathways
• Arachidonic acid metabolism
• Toxoplasmosis