CD35781

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD35781

CD35781

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Prkag3

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• protein kinase, AMP-activated, gamma 3 non-catatlytic subunit

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
• AMPK gamma3
• AMP-activated protein kinase gamma subunit
• AMPK subunit gamma-3
• 5'-AMP-activated protein kinase subunit gamma-3

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AMPKg3S
• AMPKg3L
• AMPKg3
• Amkg3
• Ampkg3

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/241113

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891343

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_153744

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000006542

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.166501
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.453463

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=604976

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Margit. Mahlapuu, et.al., Expression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma3 in white skeletal muscle., American journal of physiology. Endocrinology and metabolism, 2004, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/14559719
• Brian R. Barnes, et.al., The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle., The Journal of biological chemistry, 2004, 279
  http://rdf.ncbi.nlm.nih.gov/pubmed/15247217
• Carles. Cantó, et.al., Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle., Cell metabolism, 2010, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/20197054
• Atul S. Deshmukh, et.al., Role of the AMPKgamma3 isoform in hypoxia-stimulated glucose transport in glycolytic skeletal muscle., American journal of physiology. Endocrinology and metabolism, 2009, 297
  http://rdf.ncbi.nlm.nih.gov/pubmed/19826102
• D. Milan, et.al., A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle., Science (New York, N.Y.), 2000, 288
  http://rdf.ncbi.nlm.nih.gov/pubmed/10818001
• Haiyan. Yu, et.al., Cloning and characterization of mouse 5'-AMP-activated protein kinase gamma3 subunit., American journal of physiology. Cell physiology, 2004, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/14512293
• J X. Zhao, et.al., Mouse AMP-activated protein kinase gamma3 subunit R225Q mutation affecting mouse growth performance when fed a high-energy diet., Journal of animal science, 2010, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/20023137
• Stephan. Glund, et.al., Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle., Endocrinology, 2009, 150
  http://rdf.ncbi.nlm.nih.gov/pubmed/18818284
• Pablo M. Garcia-Roves, et.al., Gain-of-function R225Q mutation in AMP-activated protein kinase gamma3 subunit increases mitochondrial biogenesis in glycolytic skeletal muscle., The Journal of biological chemistry, 2008, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/18838377
• V. Amarger, et.al., Comparative sequence analysis of the PRKAG3 region between human and pig: evolution of repetitive sequences and potential new exons., Cytogenetic and genome research, 2003, 102
  http://rdf.ncbi.nlm.nih.gov/pubmed/14970697

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• http://purl.obolibrary.org/obo/GO_1904659
• glycogen biosynthetic process
  http://purl.obolibrary.org/obo/GO_0005978
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• AMP-activated protein kinase complex
  http://purl.obolibrary.org/obo/GO_0031588
• protein kinase binding
  http://purl.obolibrary.org/obo/GO_0019901
• fatty acid biosynthetic process
  http://purl.obolibrary.org/obo/GO_0006633
• AMP-activated protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004679
• lipid biosynthetic process
  http://purl.obolibrary.org/obo/GO_0008610
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04910
• http://www.genome.jp/dbget-bin/www_bget?map05410
• http://www.genome.jp/dbget-bin/www_bget?map04920

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Insulin signaling pathway
• Hypertrophic cardiomyopathy (HCM)
• Adipocytokine signaling pathway