CD37965

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD37965

CD37965

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Usp8

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• ubiquitin specific peptidase 8

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• deubiquitinating enzyme 8
• ubiquitin thiolesterase 8
• ubiquitin isopeptidase Y
• ubiquitin-specific-processing protease 8
• ubiquitin thioesterase 8
• putative deubiquitinating enzyme
• ubiquitin carboxyl-terminal hydrolase 8
• ubiquitin specific peptidase 8

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AI574262
• AW557536
• mKIAA0055
• Ubpy

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/84092

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• ubiquitin specific peptidase 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:1934029

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001252580
• https://www.ncbi.nlm.nih.gov/nuccore/NM_019729

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000027363

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.272629

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603158

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• N. Gnesutta, et.al., Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11500497
• Giovanna. Berruti, et.al., mUBPy and MSJ-1, a deubiquitinating enzyme and a molecular chaperone specifically expressed in testis, associate with the acrosome and centrosome in mouse germ cells., Annals of the New York Academy of Sciences, 2002, 973
  http://rdf.ncbi.nlm.nih.gov/pubmed/12485825
• Giovanna. Berruti, et.al., USP8, a regulator of endosomal sorting, is involved in mouse acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules., Biology of reproduction, 2010, 82
  http://rdf.ncbi.nlm.nih.gov/pubmed/20130268
• M. Kato, et.al., A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP., The Journal of biological chemistry, 2000, 275
  http://rdf.ncbi.nlm.nih.gov/pubmed/10982817
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• Ilana. Berlin, et.al., Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complex., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20736164
• Jinjin. Cai, et.al., Diacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20064931
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Noriko. Okazaki, et.al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries., DNA research : an international journal for rapid publication of reports on genes and genomes, 2003, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/12693553
• Marta. d'Amora, et.al., Expression pattern of mUBPy in the brain and sensory organs of mouse during embryonic development., Brain research, 2010, 1355
  http://rdf.ncbi.nlm.nih.gov/pubmed/20633544

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• protein K63-linked deubiquitination
  http://purl.obolibrary.org/obo/GO_0070536
• cysteine-type peptidase activity
  http://purl.obolibrary.org/obo/GO_0008234
• ubiquitin thiolesterase activity
  http://purl.obolibrary.org/obo/GO_0004221
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• protein deubiquitination
  http://purl.obolibrary.org/obo/GO_0016579
• extrinsic component of plasma membrane
  http://purl.obolibrary.org/obo/GO_0019897
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• endosome
  http://purl.obolibrary.org/obo/GO_0005768
• extrinsic component of endosome membrane
  http://purl.obolibrary.org/obo/GO_0031313
• SH3 domain binding
  http://purl.obolibrary.org/obo/GO_0017124
• cell cycle
  http://purl.obolibrary.org/obo/GO_0007049
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• ubiquitin-specific protease activity
  http://purl.obolibrary.org/obo/GO_0004843
• early endosome
  http://purl.obolibrary.org/obo/GO_0005769
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• proteolysis
  http://purl.obolibrary.org/obo/GO_0006508
• Ras protein signal transduction
  http://purl.obolibrary.org/obo/GO_0007265
• endosome organization
  http://purl.obolibrary.org/obo/GO_0007032
• peptidase activity
  http://purl.obolibrary.org/obo/GO_0008233
• ubiquitin-dependent protein catabolic process
  http://purl.obolibrary.org/obo/GO_0006511
• protein K48-linked deubiquitination
  http://purl.obolibrary.org/obo/GO_0071108

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04144

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Endocytosis