CD39170

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39170

CD39170

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Top3b

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• topoisomerase (DNA) III beta

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• DNA topoisomerase III beta-1
• DNA topoisomerase 3-beta-1
• topoisomerase (DNA) III beta

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Topo III beta

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/21976

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• topoisomerase (DNA) III beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1333803

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011624

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022779

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.326089

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603582

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Subhasis. Mohanty, et.al., Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18367668
• T. Seki, et.al., Cloning of cDNA encoding a novel mouse DNA topoisomerase III (Topo IIIbeta) possessing negatively supercoiled DNA relaxing activity, whose message is highly expressed in the testis., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9786843
• K Y. Kwan, et.al., Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11331780
• Roland H. Friedel, et.al., EUCOMM--the European conditional mouse mutagenesis program., Briefings in functional genomics & proteomics, 2007, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/17967808
• Kelvin Y. Kwan, et.al., Infertility and aneuploidy in mice lacking a type IA DNA topoisomerase III beta., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/12591952
• T M. Wilson, et.al., Cloning and characterization of Drosophila topoisomerase IIIbeta. Relaxation of hypernegatively supercoiled DNA., The Journal of biological chemistry, 2000, 275
  http://rdf.ncbi.nlm.nih.gov/pubmed/10636841
• Kelvin Y. Kwan, et.al., Development of autoimmunity in mice lacking DNA topoisomerase 3beta., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/17517607

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• chromosome segregation
  http://purl.obolibrary.org/obo/GO_0007059
• isomerase activity
  http://purl.obolibrary.org/obo/GO_0016853
• DNA topoisomerase type I activity
  http://purl.obolibrary.org/obo/GO_0003917
• condensed chromosome
  http://purl.obolibrary.org/obo/GO_0000793
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• DNA topological change
  http://purl.obolibrary.org/obo/GO_0006265
• DNA topoisomerase activity
  http://purl.obolibrary.org/obo/GO_0003916
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• chromosome
  http://purl.obolibrary.org/obo/GO_0005694

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map03460
• http://www.genome.jp/dbget-bin/www_bget?map03440

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Fanconi anemia pathway
• Homologous recombination