CD39419

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39419

CD39419

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Serpina1c

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• serine (or cysteine) peptidase inhibitor, clade A, member 1C

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• pre-elafin
• serine protease inhibitor 1-6
• serpin A1c
• alpha-1 protease inhibitor 3
• alpha-1-antitrypsin 1-3
• serine protease inhibitor 1-3
• alpha-1-antitrypsin 1-6
• serine (or cysteine) peptidase inhibitor, clade A, member 1C
• alpha-1 protease inhibitor 6
• serine (or cysteine) proteinase inhibitor, clade A, member 1c
• apha-1 protease inhibitor 3
• trappin-2
• serine protease inhibitor A1c

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Pi6
• Spi1-6
• PI6
• Spi1-3
• PI3
• Pi3
• Skalp
• Wap3

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/20702

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• serine (or cysteine) peptidase inhibitor, clade A, member 1C
  http://metadb.riken.jp/db/mgi_rdf/MGI:891969

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009245

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000079015

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.439695
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.439692
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.439694

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=107400

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• F. Borriello, et.al., Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence., Proceedings of the National Academy of Sciences of the United States of America, 1991, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/1946354
• Thomas S. Wilkinson, et.al., Trappin-2 promotes early clearance of Pseudomonas aeruginosa through CD14-dependent macrophage activation and neutrophil recruitment., The American journal of pathology, 2009, 174
  http://rdf.ncbi.nlm.nih.gov/pubmed/19264904
• http://rdf.ncbi.nlm.nih.gov/pubmed/6547997
• Ingrid G. Winkler, et.al., Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization., The Journal of experimental medicine, 2005, 201
  http://rdf.ncbi.nlm.nih.gov/pubmed/15795238
• J. Tardiff, et.al., Divergent expression of alpha1-protease inhibitor genes in mouse and human., Nucleic acids research, 1998, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/9685498
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• T. Paterson, et.al., The expression and characterization of five recombinant murine alpha 1-protease inhibitor proteins., Biochemical and biophysical research communications, 1996, 219
  http://rdf.ncbi.nlm.nih.gov/pubmed/8619829
• Sharon. Forsyth, et.al., A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins., Genomics, 2003, 81
  http://rdf.ncbi.nlm.nih.gov/pubmed/12659817
• A. de Meeus, et.al., A detailed linkage map of subtelomeric murine chromosome 12 region including the situs inversus mutation locus IV., Mammalian genome : official journal of the International Mammalian Genome Society, 1992, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/1360279
• Karen W. Barbour, et.al., The murine alpha(1)-proteinase inhibitor gene family: polymorphism, chromosomal location, and structure., Genomics, 2002, 80
  http://rdf.ncbi.nlm.nih.gov/pubmed/12408969

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• response to peptide hormone
  http://purl.obolibrary.org/obo/GO_0043434
• peptidase inhibitor activity
  http://purl.obolibrary.org/obo/GO_0030414
• negative regulation of peptidase activity
  http://purl.obolibrary.org/obo/GO_0010466
• regulation of proteolysis
  http://purl.obolibrary.org/obo/GO_0030162
• negative regulation of endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0010951
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• response to cytokine
  http://purl.obolibrary.org/obo/GO_0034097
• serine-type endopeptidase inhibitor activity
  http://purl.obolibrary.org/obo/GO_0004867

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04610

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Complement and coagulation cascades