CD39583

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39583

CD39583

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ghrl

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• ghrelin

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• preproghrelin
• motilin-related peptide
• proghrelin
• appetite-regulating hormone
• ghrelin
• growth hormone-releasing peptide
• growth hormone secretagogue

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• MTLRPAP
• 2210006E23Rik
• MTLRP
• m46

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/58991

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• ghrelin
  http://metadb.riken.jp/db/mgi_rdf/MGI:1930008

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_021488

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000064177

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.379095

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605353

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Xiaojun. Ma, et.al., Ablations of ghrelin and ghrelin receptor exhibit differential metabolic phenotypes and thermogenic capacity during aging., PloS one, 2011, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/21298106
• M. Kojima, et.al., Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor., Trends in endocrinology and metabolism: TEM, 2001, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/11306336
• C. Tomasetto, et.al., Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide., Gastroenterology, 2000, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/10930375
• Ye Lauren. Liu, et.al., Ghrelin gene expression is age-dependent and influenced by gender and the level of circulating IGF-I., Molecular and cellular endocrinology, 2002, 189
  http://rdf.ncbi.nlm.nih.gov/pubmed/12039068
• Hiroyuki. Ariyasu, et.al., Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin., Endocrinology, 2002, 143
  http://rdf.ncbi.nlm.nih.gov/pubmed/12193546
• B. Valtat, et.al., Genetic evidence of the programming of beta cell mass and function by glucocorticoids in mice., Diabetologia, 2011, 54
  http://rdf.ncbi.nlm.nih.gov/pubmed/20857084
• Pia. Nyeng, et.al., Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche., Developmental biology, 2011, 349
  http://rdf.ncbi.nlm.nih.gov/pubmed/20883684
• M. Tanaka, et.al., Testis-specific and developmentally induced expression of a ghrelin gene-derived transcript that encodes a novel polypeptide in the mouse., Biochimica et biophysica acta, 2001, 1522
  http://rdf.ncbi.nlm.nih.gov/pubmed/11718902
• Jennifer L. Plank, et.al., Influence and timing of arrival of murine neural crest on pancreatic beta cell development and maturation., Developmental biology, 2011, 349
  http://rdf.ncbi.nlm.nih.gov/pubmed/21081123
• Tadasuke. Komori, et.al., Regulation of ghrelin signaling by a leptin-induced gene, negative regulatory element-binding protein, in the hypothalamic neurons., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20876580

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0001934
• positive regulation of corticotropin secretion
  http://purl.obolibrary.org/obo/GO_0051461
• negative regulation of circadian sleep/wake cycle, REM sleep
  http://purl.obolibrary.org/obo/GO_0042322
• G-protein coupled receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007186
• regulation of response to food
  http://purl.obolibrary.org/obo/GO_0032095
• negative regulation of locomotion
  http://purl.obolibrary.org/obo/GO_0040013
• actin polymerization or depolymerization
  http://purl.obolibrary.org/obo/GO_0008154
• negative regulation of endothelial cell proliferation
  http://purl.obolibrary.org/obo/GO_0001937
• positive regulation of synapse assembly
  http://purl.obolibrary.org/obo/GO_0051965
• positive regulation of appetite
  http://purl.obolibrary.org/obo/GO_0032100
• negative regulation of inflammatory response
  http://purl.obolibrary.org/obo/GO_0050728
• positive regulation of protein tyrosine kinase activity
  http://purl.obolibrary.org/obo/GO_0061098
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• negative regulation of interleukin-6 biosynthetic process
  http://purl.obolibrary.org/obo/GO_0045409
• regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0042127
• protein tyrosine kinase activator activity
  http://purl.obolibrary.org/obo/GO_0030296
• response to estrogen
  http://purl.obolibrary.org/obo/GO_0043627
• hormone activity
  http://purl.obolibrary.org/obo/GO_0005179
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• activation of MAPK activity
  http://purl.obolibrary.org/obo/GO_0000187
• gastric acid secretion
  http://purl.obolibrary.org/obo/GO_0001696
• dendrite development
  http://purl.obolibrary.org/obo/GO_0016358
• adult feeding behavior
  http://purl.obolibrary.org/obo/GO_0008343
• growth hormone-releasing hormone activity
  http://purl.obolibrary.org/obo/GO_0016608
• visual learning
  http://purl.obolibrary.org/obo/GO_0008542
• positive regulation of circadian sleep/wake cycle, non-REM sleep
  http://purl.obolibrary.org/obo/GO_0046010
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• ghrelin receptor binding
  http://purl.obolibrary.org/obo/GO_0031768
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• positive regulation of growth hormone secretion
  http://purl.obolibrary.org/obo/GO_0060124
• positive regulation of response to food
  http://purl.obolibrary.org/obo/GO_0032097
• axon
  http://purl.obolibrary.org/obo/GO_0030424
• decidualization
  http://purl.obolibrary.org/obo/GO_0046697
• negative regulation of insulin secretion
  http://purl.obolibrary.org/obo/GO_0046676
• G-protein coupled receptor binding
  http://purl.obolibrary.org/obo/GO_0001664
• negative regulation of interleukin-1 beta production
  http://purl.obolibrary.org/obo/GO_0032691
• negative regulation of tumor necrosis factor biosynthetic process
  http://purl.obolibrary.org/obo/GO_0042536
• positive regulation of insulin secretion
  http://purl.obolibrary.org/obo/GO_0032024
• positive regulation of cortisol secretion
  http://purl.obolibrary.org/obo/GO_0051464
• response to hormone
  http://purl.obolibrary.org/obo/GO_0009725
• positive regulation of cytosolic calcium ion concentration
  http://purl.obolibrary.org/obo/GO_0007204

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04080

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Neuroactive ligand-receptor interaction