CD39700

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39700

CD39700

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pdgfa

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• platelet derived growth factor, alpha

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• platelet-derived growth factor subunit A
• PDGF subunit A
• platelet derived growth factor, alpha
• platelet-derived growth factor A chain
• platelet-derived growth factor alpha polypeptide
• PDGF-1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18590

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• platelet derived growth factor, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:97527

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008808

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000025856

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.2675

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=173430

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• T M. Wilkie, et.al., Evolution of the mammalian G protein alpha subunit multigene family., Nature genetics, 1992, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/1302014
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• http://rdf.ncbi.nlm.nih.gov/pubmed/20619341
• F. Rorsman, et.al., Characterization of the mouse PDGF A-chain gene. Evolutionary conservation of gene structure, nucleotide sequence and alternative splicing., Growth factors (Chur, Switzerland), 1992, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/1340209
• Amer. Sehic, et.al., Gene expression and dental enamel structure in developing mouse incisor., European journal of oral sciences, 2010, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/20487000
• S L. Palmieri, et.al., Expression of mouse PDGF-A and PDGF alpha-receptor genes during pre- and post-implantation development: evidence for a developmental shift from an autocrine to a paracrine mode of action., Mechanisms of development, 1992, 39
  http://rdf.ncbi.nlm.nih.gov/pubmed/1292572
• Mia. Niklasson, et.al., Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells., Experimental cell research, 2010, 316
  http://rdf.ncbi.nlm.nih.gov/pubmed/20643125
• Fenglei. He, et.al., Gsk3β is required in the epithelium for palatal elevation in mice., Developmental dynamics : an official publication of the American Association of Anatomists, 2010, 239
  http://rdf.ncbi.nlm.nih.gov/pubmed/20981831
• A. Orr-Urtreger, et.al., Platelet-derived growth factor-A and its receptor are expressed in separate, but adjacent cell layers of the mouse embryo., Development (Cambridge, England), 1992, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/1451656
• J B. Hutchins, et.al., Developmental distribution of platelet-derived growth factor in the mouse central nervous system., Brain research. Developmental brain research, 1992, 67
  http://rdf.ncbi.nlm.nih.gov/pubmed/1324805

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• lung alveolus development
  http://purl.obolibrary.org/obo/GO_0048286
• positive regulation of mesenchymal cell proliferation
  http://purl.obolibrary.org/obo/GO_0002053
• negative chemotaxis
  http://purl.obolibrary.org/obo/GO_0050919
• hair follicle development
  http://purl.obolibrary.org/obo/GO_0001942
• platelet-derived growth factor receptor binding
  http://purl.obolibrary.org/obo/GO_0005161
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• digestive tract development
  http://purl.obolibrary.org/obo/GO_0048565
• cell surface binding
  http://purl.obolibrary.org/obo/GO_0043498
• protein heterodimerization activity
  http://purl.obolibrary.org/obo/GO_0046982
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• actin cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0030036
• regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling
  http://purl.obolibrary.org/obo/GO_0060683
• positive regulation of protein autophosphorylation
  http://purl.obolibrary.org/obo/GO_0031954
• negative regulation of phosphatidylinositol biosynthetic process
  http://purl.obolibrary.org/obo/GO_0010512
• positive regulation of MAPK cascade
  http://purl.obolibrary.org/obo/GO_0043410
• positive regulation of DNA replication
  http://purl.obolibrary.org/obo/GO_0045740
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• skin development
  http://purl.obolibrary.org/obo/GO_0043588
• response to wounding
  http://purl.obolibrary.org/obo/GO_0009611
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• microvillus
  http://purl.obolibrary.org/obo/GO_0005902
• platelet-derived growth factor receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0048008
• positive regulation of ERK1 and ERK2 cascade
  http://purl.obolibrary.org/obo/GO_0070374
• platelet-derived growth factor binding
  http://purl.obolibrary.org/obo/GO_0048407
• eukaryotic cell surface binding
  http://purl.obolibrary.org/obo/GO_0043499
• positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
  http://purl.obolibrary.org/obo/GO_0035793
• cell projection assembly
  http://purl.obolibrary.org/obo/GO_0030031
• collagen binding
  http://purl.obolibrary.org/obo/GO_0005518
• positive regulation of cell migration
  http://purl.obolibrary.org/obo/GO_0030335
• regulation of peptidyl-tyrosine phosphorylation
  http://purl.obolibrary.org/obo/GO_0050730
• growth factor activity
  http://purl.obolibrary.org/obo/GO_0008083
• regulation of smooth muscle cell migration
  http://purl.obolibrary.org/obo/GO_0014910
• angiogenesis
  http://purl.obolibrary.org/obo/GO_0001525
• positive regulation of cell division
  http://purl.obolibrary.org/obo/GO_0051781
• negative regulation of platelet activation
  http://purl.obolibrary.org/obo/GO_0010544
• positive regulation of phosphatidylinositol 3-kinase signaling
  http://purl.obolibrary.org/obo/GO_0014068
• positive regulation of MAP kinase activity
  http://purl.obolibrary.org/obo/GO_0043406
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• positive regulation of protein kinase B signaling
  http://purl.obolibrary.org/obo/GO_0051897
• positive regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008284
• positive regulation of fibroblast proliferation
  http://purl.obolibrary.org/obo/GO_0048146

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04010
• http://www.genome.jp/dbget-bin/www_bget?map05202
• http://www.genome.jp/dbget-bin/www_bget?map05211
• http://www.genome.jp/dbget-bin/www_bget?map04810
• http://www.genome.jp/dbget-bin/www_bget?map05215
• http://www.genome.jp/dbget-bin/www_bget?map04510
• http://www.genome.jp/dbget-bin/www_bget?map05166
• http://www.genome.jp/dbget-bin/www_bget?map05214
• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map04060
• http://www.genome.jp/dbget-bin/www_bget?map05218
• http://www.genome.jp/dbget-bin/www_bget?map04540

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• MAPK signaling pathway
• Pathways in cancer
• HTLV-I infection
• Gap junction
• Cytokine-cytokine receptor interaction
• Transcriptional misregulation in cancers
• Regulation of actin cytoskeleton
• Prostate cancer
• Focal adhesion
• Glioma
• Renal cell carcinoma
• Melanoma