CD39771

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39771

CD39771

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Lrp5

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• low density lipoprotein receptor-related protein 5

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• low-density lipoprotein receptor-related protein 7
• low-density lipoprotein receptor-related protein 5
• LRP-5
• low density lipoprotein receptor-related protein 5
• LRP-7

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• LR3
• mKIAA4142
• HBM
• BMND1
• LRP7
• OPPG

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16973

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• low density lipoprotein receptor-related protein 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1278315

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008513

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000024913

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.274581

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603506

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• J. Mao, et.al., Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway., Molecular cell, 2001, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/11336703
• Youngwook. Ahn, et.al., Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning., Development (Cambridge, England), 2010, 137
  http://rdf.ncbi.nlm.nih.gov/pubmed/20724449
• D. Chen, et.al., Molecular cloning of mouse Lrp7(Lr3) cDNA and chromosomal mapping of orthologous genes in mouse and human., Genomics, 1999, 55
  http://rdf.ncbi.nlm.nih.gov/pubmed/10049586
• P J. Hey, et.al., Cloning of a novel member of the low-density lipoprotein receptor family., Gene, 1998, 216
  http://rdf.ncbi.nlm.nih.gov/pubmed/9714764
• Chun-hong. Xia, et.al., LRP5 is required for vascular development in deeper layers of the retina., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/20652025
• Masaki. Kato, et.al., Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor., The Journal of cell biology, 2002, 157
  http://rdf.ncbi.nlm.nih.gov/pubmed/11956231
• Jolie L. Chang, et.al., Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-β and Runx2 in bone is required for hearing., EMBO reports, 2010, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/20847738
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• http://rdf.ncbi.nlm.nih.gov/pubmed/21061374
• K I. Pinson, et.al., An LDL-receptor-related protein mediates Wnt signalling in mice., Nature, 2000, 407
  http://rdf.ncbi.nlm.nih.gov/pubmed/11029008

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0051091
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cholesterol metabolic process
  http://purl.obolibrary.org/obo/GO_0008203
• extracellular matrix-cell signaling
  http://purl.obolibrary.org/obo/GO_0035426
• embryonic retina morphogenesis in camera-type eye
  http://purl.obolibrary.org/obo/GO_0060059
• receptor complex
  http://purl.obolibrary.org/obo/GO_0043235
• bone marrow development
  http://purl.obolibrary.org/obo/GO_0048539
• embryonic digit morphogenesis
  http://purl.obolibrary.org/obo/GO_0042733
• positive regulation of osteoblast proliferation
  http://purl.obolibrary.org/obo/GO_0033690
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• vasculature development
  http://purl.obolibrary.org/obo/GO_0001944
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• regulation of bone remodeling
  http://purl.obolibrary.org/obo/GO_0046850
• regulation of ossification
  http://purl.obolibrary.org/obo/GO_0030278
• cholesterol homeostasis
  http://purl.obolibrary.org/obo/GO_0042632
• retina morphogenesis in camera-type eye
  http://purl.obolibrary.org/obo/GO_0060042
• negative regulation of protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0071901
• canonical Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0060070
• coreceptor activity
  http://purl.obolibrary.org/obo/GO_0015026
• osteoblast development
  http://purl.obolibrary.org/obo/GO_0002076
• regulation of blood pressure
  http://purl.obolibrary.org/obo/GO_0008217
• limb morphogenesis
  http://purl.obolibrary.org/obo/GO_0035108
• regulation of insulin secretion involved in cellular response to glucose stimulus
  http://purl.obolibrary.org/obo/GO_0061178
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• positive regulation of mesenchymal cell proliferation
  http://purl.obolibrary.org/obo/GO_0002053
• Wnt signaling pathway involved in dorsal/ventral axis specification
  http://purl.obolibrary.org/obo/GO_0044332
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• bone development
  http://purl.obolibrary.org/obo/GO_0060348
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• positive regulation of mitotic nuclear division
  http://purl.obolibrary.org/obo/GO_0045840
• Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0016055
• regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0042981
• cell migration involved in gastrulation
  http://purl.obolibrary.org/obo/GO_0042074
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• anterior/posterior pattern specification
  http://purl.obolibrary.org/obo/GO_0009952
• negative regulation of osteoblast differentiation
  http://purl.obolibrary.org/obo/GO_0045668
• adipose tissue development
  http://purl.obolibrary.org/obo/GO_0060612
• retina vasculature morphogenesis in camera-type eye
  http://purl.obolibrary.org/obo/GO_0061299
• positive regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008284
• regulation of canonical Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0060828
• anatomical structure regression
  http://purl.obolibrary.org/obo/GO_0060033
• branching involved in mammary gland duct morphogenesis
  http://purl.obolibrary.org/obo/GO_0060444
• regulation of fat cell differentiation
  http://purl.obolibrary.org/obo/GO_0045598
• glucose catabolic process
  http://purl.obolibrary.org/obo/GO_0006007
• retinal blood vessel morphogenesis
  http://purl.obolibrary.org/obo/GO_0061304
• cell-cell signaling involved in mammary gland development
  http://purl.obolibrary.org/obo/GO_0060764
• gastrulation with mouth forming second
  http://purl.obolibrary.org/obo/GO_0001702
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• positive regulation of fat cell differentiation
  http://purl.obolibrary.org/obo/GO_0045600
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• Wnt-activated receptor activity
  http://purl.obolibrary.org/obo/GO_0042813
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• bone morphogenesis
  http://purl.obolibrary.org/obo/GO_0060349
• endocytosis
  http://purl.obolibrary.org/obo/GO_0006897
• Wnt-protein binding
  http://purl.obolibrary.org/obo/GO_0017147
• mammary gland duct morphogenesis
  http://purl.obolibrary.org/obo/GO_0060603
• bone remodeling
  http://purl.obolibrary.org/obo/GO_0046849
• embryonic camera-type eye morphogenesis
  http://purl.obolibrary.org/obo/GO_0048596

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04310

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Wnt signaling pathway