CD39872

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39872

CD39872

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ptges

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• prostaglandin E synthase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• prostaglandin E synthase
• microsomal prostaglandin E synthase 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• D2Ertd369e
• 2410099E23Rik
• Pges
• mPGES
• mPGES-1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/64292

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• prostaglandin E synthase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927593

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_022415

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000050737

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.28768

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605172

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Satoshi. Uematsu, et.al., Lipopolysaccharide-dependent prostaglandin E(2) production is regulated by the glutathione-dependent prostaglandin E(2) synthase gene induced by the Toll-like receptor 4/MyD88/NF-IL6 pathway., Journal of immunology (Baltimore, Md. : 1950), 2002, 168
  http://rdf.ncbi.nlm.nih.gov/pubmed/12023384
• Hussein A. Abbas, et.al., Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity., Cell stem cell, 2010, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/21040902
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Marjolaine. Gosset, et.al., Inhibition of matrix metalloproteinase-3 and -13 synthesis induced by IL-1beta in chondrocytes from mice lacking microsomal prostaglandin E synthase-1., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20943996
• Dong-juan. Zhang, et.al., Enhanced pressor response to acute Ang II infusion in mice lacking membrane-associated prostaglandin E2 synthase-1., Acta pharmacologica Sinica, 2010, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/20871624
• Michael. Lazarus, et.al., Immunohistochemical localization of microsomal PGE synthase-1 and cyclooxygenases in male mouse reproductive organs., Endocrinology, 2002, 143
  http://rdf.ncbi.nlm.nih.gov/pubmed/12021206
• Christian. Brenneis, et.al., Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation., The Journal of biological chemistry, 2011, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/21075851
• Y. Guan, et.al., Urogenital distribution of a mouse membrane-associated prostaglandin E(2) synthase., American journal of physiology. Renal physiology, 2001, 281
  http://rdf.ncbi.nlm.nih.gov/pubmed/11704570
• M. Murakami, et.al., Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2., The Journal of biological chemistry, 2000, 275
  http://rdf.ncbi.nlm.nih.gov/pubmed/10869354
• Michael. Lazarus, et.al., Biochemical characterization of mouse microsomal prostaglandin E synthase-1 and its colocalization with cyclooxygenase-2 in peritoneal macrophages., Archives of biochemistry and biophysics, 2002, 397
  http://rdf.ncbi.nlm.nih.gov/pubmed/11795891

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• prostaglandin-D synthase activity
  http://purl.obolibrary.org/obo/GO_0004667
• lipid biosynthetic process
  http://purl.obolibrary.org/obo/GO_0008610
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• prostaglandin-E synthase activity
  http://purl.obolibrary.org/obo/GO_0050220
• isomerase activity
  http://purl.obolibrary.org/obo/GO_0016853
• fatty acid biosynthetic process
  http://purl.obolibrary.org/obo/GO_0006633
• negative regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008285
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• nuclear envelope lumen
  http://purl.obolibrary.org/obo/GO_0005641
• glutathione binding
  http://purl.obolibrary.org/obo/GO_0043295
• prostaglandin metabolic process
  http://purl.obolibrary.org/obo/GO_0006693
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• microsome
  http://purl.obolibrary.org/obo/GO_0005792
• prostaglandin biosynthetic process
  http://purl.obolibrary.org/obo/GO_0001516

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map01100
• http://www.genome.jp/dbget-bin/www_bget?map00590

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Arachidonic acid metabolism
• Metabolic pathways