CD40167

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD40167

CD40167

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Abcb4

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• ATP-binding cassette, sub-family B (MDR/TAP), member 4

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• P glycoprotein 2
• ATP-binding cassette, sub-family B (MDR/TAP), member 4
• ATP-binding cassette sub-family B member 4
• multidrug resistance protein 2
• P-glycoprotein 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Mdr2
• Pgy-2
• Pgy2
• mdr-2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18670

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• ATP-binding cassette, sub-family B (MDR/TAP), member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:97569

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008830

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000042476

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.297825

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=171060

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Hila. Barash, et.al., Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20133864
• M. Raymond, et.al., Cell-specific activity of cis-acting regulatory elements in the promoter of the mouse multidrug resistance gene mdr1., Molecular and cellular biology, 1990, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/2248681
• R. Dhir, et.al., Structural and functional characterization of the mouse multidrug resistance gene family., Bulletin du cancer, 1990, 77
  http://rdf.ncbi.nlm.nih.gov/pubmed/1980424
• M. Raymond, et.al., Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells., Molecular and cellular biology, 1990, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/1969609
• Naama. Klopstock, et.al., HCV tumor promoting effect is dependent on host genetic background., PloS one, 2009, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/19340302
• E. Buschman, et.al., mdr2 encodes P-glycoprotein expressed in the bile canalicular membrane as determined by isoform-specific antibodies., The Journal of biological chemistry, 1992, 267
  http://rdf.ncbi.nlm.nih.gov/pubmed/1381362
• Eleonora. Patsenker, et.al., Inhibition of integrin alphavbeta6 on cholangiocytes blocks transforming growth factor-beta activation and retards biliary fibrosis progression., Gastroenterology, 2008, 135
  http://rdf.ncbi.nlm.nih.gov/pubmed/18538673
• Ingo. Strack, et.al., β-Adrenoceptor blockade in sclerosing cholangitis of Mdr2 knockout mice: antifibrotic effects in a model of nonsinusoidal fibrosis., Laboratory investigation; a journal of technical methods and pathology, 2011, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/20921947
• http://rdf.ncbi.nlm.nih.gov/pubmed/2069718

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• transmembrane transport
  http://purl.obolibrary.org/obo/GO_0055085
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• apical plasma membrane
  http://purl.obolibrary.org/obo/GO_0016324
• ATPase activity
  http://purl.obolibrary.org/obo/GO_0016887
• nucleoside-triphosphatase activity
  http://purl.obolibrary.org/obo/GO_0017111
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• Golgi membrane
  http://purl.obolibrary.org/obo/GO_0000139
• ATPase activity, coupled to transmembrane movement of substances
  http://purl.obolibrary.org/obo/GO_0042626
• intercellular canaliculus
  http://purl.obolibrary.org/obo/GO_0046581
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map02010
• http://www.genome.jp/dbget-bin/www_bget?map04976

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• ABC transporters
• Bile secretion