CD40484

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD40484

CD40484

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Slc10a1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• solute carrier family 10 (sodium/bile acid cotransporter family), member 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• sodium/taurocholate cotransporting polypeptide
• sodium/bile acid cotransporter
• solute carrier family 10 (sodium/bile acid cotransporter family), member 1
• Na(+)/taurocholate transport protein
• bile acid cotransporting polypeptide
• Na(+)/bile acid cotransporter
• sodium-taurocholate cotransporting polypeptide

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• sodium bile acid cotransporting polypeptide
• Ntcp

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/20493

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• solute carrier family 10 (sodium/bile acid cotransporter family), member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97379

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001177561
• https://www.ncbi.nlm.nih.gov/nuccore/NM_011387

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000021135

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.341781

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=182396

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• E C. Torchia, et.al., Coordinate regulation of bile acid biosynthetic and recovery pathways., Biochemical and biophysical research communications, 1996, 225
  http://rdf.ncbi.nlm.nih.gov/pubmed/8769105
• N R. Koopen, et.al., Decreased Na+-dependent taurocholate uptake and low expression of the sinusoidal Na+-taurocholate cotransporting protein (Ntcp) in livers of mdr2 P-glycoprotein-deficient mice., Journal of hepatology, 1999, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/9927146
• Iván L. Csanaky, et.al., Role of hepatic transporters in prevention of bile acid toxicity after partial hepatectomy in mice., American journal of physiology. Gastrointestinal and liver physiology, 2009, 297
  http://rdf.ncbi.nlm.nih.gov/pubmed/19497955
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Xingguo. Cheng, et.al., Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers., Toxicological sciences : an official journal of the Society of Toxicology, 2008, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/18703564
• B. Hagenbuch, et.al., Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system., Proceedings of the National Academy of Sciences of the United States of America, 1991, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/1961729
• Maria H. Festing, et.al., Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1., Genesis (New York, N.Y. : 2000), 2009, 47
  http://rdf.ncbi.nlm.nih.gov/pubmed/19882669
• B. Hagenbuch, et.al., Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter., The Journal of clinical investigation, 1994, 93
  http://rdf.ncbi.nlm.nih.gov/pubmed/8132774
• Satoki. Imai, et.al., Analysis of DNA methylation and histone modification profiles of liver-specific transporters., Molecular pharmacology, 2009, 75
  http://rdf.ncbi.nlm.nih.gov/pubmed/19047482
• R M. Green, et.al., Genetic mapping of the Na(+)-taurocholate cotransporting polypeptide to mouse chromosome 12., Mammalian genome : official journal of the International Mammalian Genome Society, 1998, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/9657862

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• bile acid:sodium symporter activity
  http://purl.obolibrary.org/obo/GO_0008508
• basolateral plasma membrane
  http://purl.obolibrary.org/obo/GO_0016323
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• bile acid transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0015125
• transmembrane transport
  http://purl.obolibrary.org/obo/GO_0055085
• sodium ion transport
  http://purl.obolibrary.org/obo/GO_0006814
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• symporter activity
  http://purl.obolibrary.org/obo/GO_0015293
• bile acid and bile salt transport
  http://purl.obolibrary.org/obo/GO_0015721
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• ion transport
  http://purl.obolibrary.org/obo/GO_0006811
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• organic anion transport
  http://purl.obolibrary.org/obo/GO_0015711
• sodium ion export from cell
  http://purl.obolibrary.org/obo/GO_0036376

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04976

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Bile secretion