CD40510

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD40510

CD40510

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pdcd1lg2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• programmed cell death 1 ligand 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• PDCD1 ligand 2
• butyrophilin-like protein
• PD-1 ligand 2
• programmed death ligand 2
• butyrophilin B7-DC
• programmed cell death 1 ligand 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Btdc
• PD-L2
• B7-DC
• F730015O22Rik

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/58205

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• programmed cell death 1 ligand 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1930125

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_021396

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000016498

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.116737

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605723

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Kenji. Ishiwata, et.al., Costimulator B7-DC attenuates strong Th2 responses induced by Nippostrongylus brasiliensis., Journal of immunology (Baltimore, Md. : 1950), 2010, 184
  http://rdf.ncbi.nlm.nih.gov/pubmed/20065112
• S Y. Tseng, et.al., B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells., The Journal of experimental medicine, 2001, 193
  http://rdf.ncbi.nlm.nih.gov/pubmed/11283156
• Silke. Huber, et.al., Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20625006
• Sariah J. Allen, et.al., The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1., Journal of virology, 2011, 85
  http://rdf.ncbi.nlm.nih.gov/pubmed/21307196
• Masayoshi. Ishida, et.al., Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues., Immunology letters, 2002, 84
  http://rdf.ncbi.nlm.nih.gov/pubmed/12161284
• Engin. Ozkaynak, et.al., Programmed death-1 targeting can promote allograft survival., Journal of immunology (Baltimore, Md. : 1950), 2002, 169
  http://rdf.ncbi.nlm.nih.gov/pubmed/12444166
• Y. Latchman, et.al., PD-L2 is a second ligand for PD-1 and inhibits T cell activation., Nature immunology, 2001, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/11224527
• Tomohide. Yamazaki, et.al., Expression of programmed death 1 ligands by murine T cells and APC., Journal of immunology (Baltimore, Md. : 1950), 2002, 169
  http://rdf.ncbi.nlm.nih.gov/pubmed/12421930
• Tomohiro. Fukaya, et.al., Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4+Foxp3+ regulatory T cells in the establishment of oral tolerance., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20574047
• Kim L. Good-Jacobson, et.al., PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells., Nature immunology, 2010, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/20453843

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• negative regulation of T cell proliferation
  http://purl.obolibrary.org/obo/GO_0042130
• positive regulation of T cell proliferation
  http://purl.obolibrary.org/obo/GO_0042102
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04514

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Cell adhesion molecules (CAMs)