CD40835

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD40835

CD40835

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Mep1a

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• meprin 1 alpha

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• meprin A subunit alpha
• meprin 1 alpha
• endopeptidase-2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• meprin A alpha-subunit
• Mep-1
• Mep1
• AI098089
• Mep-1a
• meprin alpha
• AW107200

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/17287

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• meprin 1 alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:96963

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008585

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000023914

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.5346

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=600388

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• C M. Gorbea, et.al., Homo- and heterotetrameric forms of the membrane-bound metalloendopeptidases meprin A and B., Archives of biochemistry and biophysics, 1991, 290
  http://rdf.ncbi.nlm.nih.gov/pubmed/1929422
• E. Dumermuth, et.al., The astacin family of metalloendopeptidases., The Journal of biological chemistry, 1991, 266
  http://rdf.ncbi.nlm.nih.gov/pubmed/1939172
• S S. Craig, et.al., Immunohistochemical localization of the metalloproteinase meprin in salivary glands of male and female mice., The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1991, 39
  http://rdf.ncbi.nlm.nih.gov/pubmed/1701182
• Qi. Sun, et.al., Disruption of the meprin alpha and beta genes in mice alters homeostasis of monocytes and natural killer cells., Experimental hematology, 2009, 37
  http://rdf.ncbi.nlm.nih.gov/pubmed/19110362
• S. Banerjee, et.al., MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease., Mucosal immunology, 2009, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/19262505
• Renee E. Yura, et.al., Meprin A metalloproteases enhance renal damage and bladder inflammation after LPS challenge., American journal of physiology. Renal physiology, 2009, 296
  http://rdf.ncbi.nlm.nih.gov/pubmed/18971209
• R L. Wolz, et.al., Mapping the active site of meprin-A with peptide substrates and inhibitors., Biochemistry, 1991, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/1883833
• W. Jiang, et.al., The alpha subunit of meprin A. Molecular cloning and sequencing, differential expression in inbred mouse strains, and evidence for divergent evolution of the alpha and beta subunits., The Journal of biological chemistry, 1992, 267
  http://rdf.ncbi.nlm.nih.gov/pubmed/1374387
• Sanjita. Banerjee, et.al., Balance of meprin A and B in mice affects the progression of experimental inflammatory bowel disease., American journal of physiology. Gastrointestinal and liver physiology, 2011, 300
  http://rdf.ncbi.nlm.nih.gov/pubmed/21071511
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• meprin A complex
  http://purl.obolibrary.org/obo/GO_0017090
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• proteolysis
  http://purl.obolibrary.org/obo/GO_0006508
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• peptidase activity
  http://purl.obolibrary.org/obo/GO_0008233
• metalloendopeptidase activity
  http://purl.obolibrary.org/obo/GO_0004222
• metallopeptidase activity
  http://purl.obolibrary.org/obo/GO_0008237

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04974

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Protein digestion and absorption