CD40866

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD40866

CD40866

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pde6h

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• phosphodiesterase 6H, cGMP-specific, cone, gamma

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
• cone-like cGMP-phosphodiesterase 6 gamma subunit type 2
• phosphodiesterase 6H, cGMP-specific, cone, gamma
• GMP-PDE gamma
• cone phosphodiesterase 6 gamma

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• A930033D18Rik
• PDEgamma

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/78600

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• phosphodiesterase 6H, cGMP-specific, cone, gamma
  http://metadb.riken.jp/db/mgi_rdf/MGI:1925850

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_023898

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000064330

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.290622

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601190

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Joseph C. Corbo, et.al., A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome., PLoS genetics, 2005, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/16110338
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Rothwelle J. Tate, et.al., The identification of the inhibitory gamma-subunits of the type 6 retinal cyclic guanosine monophosphate phosphodiesterase in non-retinal tissues: differential processing of mRNA transcripts., Genomics, 2002, 79
  http://rdf.ncbi.nlm.nih.gov/pubmed/11944991
• Hiroki. Fujieda, et.al., Retinoic acid receptor-related orphan receptor alpha regulates a subset of cone genes during mouse retinal development., Journal of neurochemistry, 2009, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/19014374
• Kenji. Omori, et.al., Overview of PDEs and their regulation., Circulation research, 2007, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/17307970
• Li. Jia, et.al., Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19805139
• Brandy. Barren, et.al., Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit., The EMBO journal, 2009, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/19798052
• Kerstin M. Janisch, et.al., Light-dependent phosphorylation of the gamma subunit of cGMP-phophodiesterase (PDE6gamma) at residue threonine 22 in intact photoreceptor neurons., Biochemical and biophysical research communications, 2009, 390
  http://rdf.ncbi.nlm.nih.gov/pubmed/19878658
• K F. Wan, et.al., The inhibitory gamma subunit of the type 6 retinal cyclic guanosine monophosphate phosphodiesterase is a novel intermediate regulating p42/p44 mitogen-activated protein kinase signaling in human embryonic kidney 293 cells., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11502744
• Steven H. Tsang, et.al., GAP-independent termination of photoreceptor light response by excess gamma subunit of the cGMP-phosphodiesterase., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/16641226

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of epidermal growth factor receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0045742
• response to stimulus
  http://purl.obolibrary.org/obo/GO_0050896
• positive regulation of G-protein coupled receptor protein signaling pathway
  http://purl.obolibrary.org/obo/GO_0045745
• visual perception
  http://purl.obolibrary.org/obo/GO_0007601
• activation of MAPK activity
  http://purl.obolibrary.org/obo/GO_0000187
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• cGMP binding
  http://purl.obolibrary.org/obo/GO_0030553

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00230

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Purine metabolism