CD41123

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD41123

CD41123

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Sharpin

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• SHANK-associated RH domain interacting protein

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• SHANK-associated RH domain interacting protein
• protein kinase C-interacting protein RBCC like 1
• shank-interacting protein-like 1
• mSIPL1
• shank-associated RH domain-interacting protein
• sharpin

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• cpdm
• SIPL1
• RBCKL1
• AW121341
• 0610041B22Rik

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/106025

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• SHANK-associated RH domain interacting protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913331

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_025340

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022552

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.41463

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=611885

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• http://rdf.ncbi.nlm.nih.gov/pubmed/7792947
• Harm. HogenEsch, et.al., Expression of chitinase-like proteins in the skin of chronic proliferative dermatitis (cpdm/cpdm) mice., Experimental dermatology, 2006, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/16984263
• Yanhua. Liang, et.al., Inhibition of NF-κB signaling retards eosinophilic dermatitis in SHARPIN-deficient mice., The Journal of investigative dermatology, 2011, 131
  http://rdf.ncbi.nlm.nih.gov/pubmed/20811394
• Corinna. Sawallisch, et.al., The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19208628
• H. HogenEsch, et.al., A spontaneous mutation characterized by chronic proliferative dermatitis in C57BL mice., The American journal of pathology, 1993, 143
  http://rdf.ncbi.nlm.nih.gov/pubmed/8362989
• Johann E. Gudjonsson, et.al., Mouse models of psoriasis., The Journal of investigative dermatology, 2007, 127
  http://rdf.ncbi.nlm.nih.gov/pubmed/17429444
• M J. Gijbels, et.al., Maintenance of donor phenotype after full-thickness skin transplantation from mice with chronic proliferative dermatitis (cpdm/cpdm) to C57BL/Ka and nude mice and vice versa., The Journal of investigative dermatology, 1995, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/7490470
• H I. Gallardo Torres, et.al., Chronic proliferative dermatitis in mice: neutrophil-endothelium interactions and the role of adhesion molecules., Pathobiology : journal of immunopathology, molecular and cellular biology, 1995, 63
  http://rdf.ncbi.nlm.nih.gov/pubmed/8738473
• M J. Gijbels, et.al., Pathogenesis of skin lesions in mice with chronic proliferative dermatitis (cpdm/cpdm)., The American journal of pathology, 1996, 148
  http://rdf.ncbi.nlm.nih.gov/pubmed/8774148
• R E. Seymour, et.al., Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis., Genes and immunity, 2007, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/17538631

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• protein homooligomerization
  http://purl.obolibrary.org/obo/GO_0051260
• dendrite
  http://purl.obolibrary.org/obo/GO_0030425
• negative regulation of inflammatory response
  http://purl.obolibrary.org/obo/GO_0050728
• protein linear polyubiquitination
  http://purl.obolibrary.org/obo/GO_0097039
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• identical protein binding
  http://purl.obolibrary.org/obo/GO_0042802
• apoptotic nuclear changes
  http://purl.obolibrary.org/obo/GO_0030262
• postsynaptic density
  http://purl.obolibrary.org/obo/GO_0014069
• epidermis development
  http://purl.obolibrary.org/obo/GO_0008544
• regulation of tumor necrosis factor-mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0010803
• keratinization
  http://purl.obolibrary.org/obo/GO_0031424
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• mitochondrion organization
  http://purl.obolibrary.org/obo/GO_0007005
• regulation of CD40 signaling pathway
  http://purl.obolibrary.org/obo/GO_2000348
• positive regulation of I-kappaB kinase/NF-kappaB signaling
  http://purl.obolibrary.org/obo/GO_0043123
• macromolecular complex binding
  http://purl.obolibrary.org/obo/GO_0044877
• LUBAC complex
  http://purl.obolibrary.org/obo/GO_0071797

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName