CD41694

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD41694

CD41694

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Fyb

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• FYN binding protein

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• FYN binding protein
• FYN-T-binding protein
• FYN-binding protein
• SLAP-130
• SLAP130
• SLP-76-associated phosphoprotein
他3件を見る
• adhesion and degranulation promoting adaptor protein
• p120/130
• p120/p130

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• ADAP
• B630013F22Rik
• FYB-120/130

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/23880

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• FYN binding protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346327

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011815

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022148

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.170905

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602731

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• J F. Timms, et.al., SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages., Current biology : CB, 1999, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/10469599
• M. Veale, et.al., Novel isoform of lymphoid adaptor FYN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 production., The Journal of biological chemistry, 1999, 274
  http://rdf.ncbi.nlm.nih.gov/pubmed/10497204
• M. Krause, et.al., Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton., The Journal of cell biology, 2000, 149
  http://rdf.ncbi.nlm.nih.gov/pubmed/10747096
• D S. Black, et.al., The Yersinia tyrosine phosphatase YopH targets a novel adhesion-regulated signalling complex in macrophages., Cellular microbiology, 2000, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/11207596
• Ana. Kasirer-Friede, et.al., Role for ADAP in shear flow-induced platelet mechanotransduction., Blood, 2010, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/19996090
• Rupa. Srivastava, et.al., NF-kappaB activation in T cells requires discrete control of IkappaB kinase alpha/beta (IKKalpha/beta) phosphorylation and IKKgamma ubiquitination by the ADAP adapter protein., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20164171
他4件を見る
• Marc. Sylvester, et.al., Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/20661443
• Irene M. Patzak, et.al., HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion., European journal of immunology, 2010, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/20957749
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• A J. da Silva, et.al., Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9207119

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• macromolecular complex binding
  http://purl.obolibrary.org/obo/GO_0044877
• mast cell activation
  http://purl.obolibrary.org/obo/GO_0045576

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName