CD41943

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD41943

CD41943

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Kit

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• kit oncogene

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• proto-oncogene c-Kit
• c-kit proto-oncogene protein
• mast/stem cell growth factor receptor Kit
• spotted sterile male
• tyrosine-protein kinase Kit
• kit oncogene
• proto-oncogene tyrosine-protein kinase Kit
• SCFR
• dominant spotting

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• SCO1
• Tr-kit
• belly-spot
• SOW3
• Dominant white spotting
• SCO5
• Gsfsco1
• Gsfsco5
• Fdc
• CD117
• Gsfsow3
• Bs
• Steel Factor Receptor
• W
• c-KIT
• Ssm

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16590

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• KIT proto-oncogene receptor tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96677

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001122733
• https://www.ncbi.nlm.nih.gov/nuccore/NM_021099

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000005672

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.247073

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=164920

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Mousa. Komai-Koma, et.al., IL-33 activates B1 cells and exacerbates contact sensitivity., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21239718
• Eric J. Albert, et.al., Tissue eosinophilia in a mouse model of colitis is highly dependent on TLR2 and independent of mast cells., The American journal of pathology, 2011, 178
  http://rdf.ncbi.nlm.nih.gov/pubmed/21224053
• S J. Sharkis, et.al., Antitheta-sensitive regulatory cell (TSRC) and hematopoiesis: regulation of differentiation of transplanted stem cells in W/Wv anemic and normal mice., Blood, 1978, 52
  http://rdf.ncbi.nlm.nih.gov/pubmed/28803
• Yue-Ying. Wang, et.al., C-KIT mutation cooperates with full-length AML1-ETO to induce acute myeloid leukemia in mice., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21262832
• David A. Mancardi, et.al., Cutting Edge: The murine high-affinity IgG receptor FcγRIV is sufficient for autoantibody-induced arthritis., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21248252
• Y. Kitamura, et.al., Decreased production of mast cells in S1/S1d anemic mice., Blood, 1979, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/367470
• T W. Poole, et.al., Capacity of adult steel (SI/SId) and dominant spotting (W/Wv) mouse skin to support melanogenesis., Developmental biology, 1979, 72
  http://rdf.ncbi.nlm.nih.gov/pubmed/389712
• T C. Mayer, Interactions between normal and pigment cell populations mutant at the dominant-spotting (W) and steel (Sl) loci in the mouse., The Journal of experimental zoology, 1979, 210
  http://rdf.ncbi.nlm.nih.gov/pubmed/536714
• http://rdf.ncbi.nlm.nih.gov/pubmed/469229
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of Notch signaling pathway
  http://purl.obolibrary.org/obo/GO_0045747
• positive regulation of JAK-STAT cascade
  http://purl.obolibrary.org/obo/GO_0046427
• positive regulation of long-term neuronal synaptic plasticity
  http://purl.obolibrary.org/obo/GO_0048170
• pigmentation
  http://purl.obolibrary.org/obo/GO_0043473
• response to radiation
  http://purl.obolibrary.org/obo/GO_0009314
• spermatid development
  http://purl.obolibrary.org/obo/GO_0007286
• protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004672
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• positive regulation of cell migration
  http://purl.obolibrary.org/obo/GO_0030335
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• spermatogenesis
  http://purl.obolibrary.org/obo/GO_0007283
• intracellular signal transduction
  http://purl.obolibrary.org/obo/GO_0035556
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• positive regulation of tyrosine phosphorylation of STAT protein
  http://purl.obolibrary.org/obo/GO_0042531
• transmembrane receptor protein tyrosine kinase activity
  http://purl.obolibrary.org/obo/GO_0004714
• protein autophosphorylation
  http://purl.obolibrary.org/obo/GO_0046777
• developmental pigmentation
  http://purl.obolibrary.org/obo/GO_0048066
• epithelial cell proliferation
  http://purl.obolibrary.org/obo/GO_0050673
• positive regulation of MAP kinase activity
  http://purl.obolibrary.org/obo/GO_0043406
• positive regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010628
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• germ cell migration
  http://purl.obolibrary.org/obo/GO_0008354
• glycosphingolipid metabolic process
  http://purl.obolibrary.org/obo/GO_0006687
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• protease binding
  http://purl.obolibrary.org/obo/GO_0002020
• cytoplasmic side of plasma membrane
  http://purl.obolibrary.org/obo/GO_0009898
• positive regulation of pseudopodium assembly
  http://purl.obolibrary.org/obo/GO_0031274
• positive regulation of MAPK cascade
  http://purl.obolibrary.org/obo/GO_0043410
• cell differentiation
  http://purl.obolibrary.org/obo/GO_0030154
• transmembrane receptor protein tyrosine kinase signaling pathway
  http://purl.obolibrary.org/obo/GO_0007169
• chemotaxis
  http://purl.obolibrary.org/obo/GO_0006935
• visual learning
  http://purl.obolibrary.org/obo/GO_0008542
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• external side of plasma membrane
  http://purl.obolibrary.org/obo/GO_0009897
• acrosomal vesicle
  http://purl.obolibrary.org/obo/GO_0001669
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• myeloid progenitor cell differentiation
  http://purl.obolibrary.org/obo/GO_0002318
• positive regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008284
• positive regulation of sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0051091
• somatic stem cell division
  http://purl.obolibrary.org/obo/GO_0048103
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• germ cell development
  http://purl.obolibrary.org/obo/GO_0007281
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• negative regulation of programmed cell death
  http://purl.obolibrary.org/obo/GO_0043069
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• cytokine-mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0019221
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• activation of MAPK activity
  http://purl.obolibrary.org/obo/GO_0000187
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• stem cell factor receptor activity
  http://purl.obolibrary.org/obo/GO_0005020
• lymphoid progenitor cell differentiation
  http://purl.obolibrary.org/obo/GO_0002320
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• hemopoiesis
  http://purl.obolibrary.org/obo/GO_0030097
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• protein tyrosine kinase activity
  http://purl.obolibrary.org/obo/GO_0004713
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• peptidyl-tyrosine phosphorylation
  http://purl.obolibrary.org/obo/GO_0018108
• cytokine binding
  http://purl.obolibrary.org/obo/GO_0019955
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• regulation of developmental pigmentation
  http://purl.obolibrary.org/obo/GO_0048070
• myeloid leukocyte differentiation
  http://purl.obolibrary.org/obo/GO_0002573

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04060
• http://www.genome.jp/dbget-bin/www_bget?map04916
• http://www.genome.jp/dbget-bin/www_bget?map04144
• http://www.genome.jp/dbget-bin/www_bget?map05221
• http://www.genome.jp/dbget-bin/www_bget?map04640
• http://www.genome.jp/dbget-bin/www_bget?map05200

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Acute myeloid leukemia
• Cytokine-cytokine receptor interaction
• Melanogenesis
• Endocytosis
• Hematopoietic cell lineage
• Pathways in cancer