CD42056

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD42056

CD42056

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pnpt1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• polyribonucleotide nucleotidyltransferase 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• polyribonucleotide nucleotidyltransferase 1
• PNPase old-35
• 3'-5' RNA exonuclease OLD35
• polyribonucleotide nucleotidyltransferase 1, mitochondrial
• polynucleotide phosphorylase-like protein
• PNPase 1
• polynucleotide phosphorylase 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 1200003F12Rik
• PNPase
• polynucleotide phosphorylase
• RP23-313I4.2
• Old35
• Pnptl1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/71701

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• polyribonucleotide nucleotidyltransferase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1918951

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_027869

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000020464

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.211131

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=610316

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• David J. Pagliarini, et.al., A mitochondrial protein compendium elucidates complex I disease biology., Cell, 2008, 134
  http://rdf.ncbi.nlm.nih.gov/pubmed/18614015
• Hsiao-Wen. Chen, et.al., Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis., Molecular and cellular biology, 2006, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/16966381
• Geng. Wang, et.al., PNPASE regulates RNA import into mitochondria., Cell, 2010, 142
  http://rdf.ncbi.nlm.nih.gov/pubmed/20691904
• Reinout. Raijmakers, et.al., Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring., Journal of molecular biology, 2002, 323
  http://rdf.ncbi.nlm.nih.gov/pubmed/12419256
• Susan. Magdaleno, et.al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system., PLoS biology, 2006, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/16602821
• Adrienne E. McKee, et.al., A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain., BMC developmental biology, 2005, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/16033648

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• mitochondrion morphogenesis
  http://purl.obolibrary.org/obo/GO_0070584
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• positive regulation of mitochondrial RNA catabolic process
  http://purl.obolibrary.org/obo/GO_0000962
• mitochondrial mRNA catabolic process
  http://purl.obolibrary.org/obo/GO_0000958
• negative regulation of growth
  http://purl.obolibrary.org/obo/GO_0045926
• cellular response to interferon-beta
  http://purl.obolibrary.org/obo/GO_0035458
• mRNA polyadenylation
  http://purl.obolibrary.org/obo/GO_0006378
• miRNA binding
  http://purl.obolibrary.org/obo/GO_0035198
• RNA binding
  http://purl.obolibrary.org/obo/GO_0003723
• cellular response to oxidative stress
  http://purl.obolibrary.org/obo/GO_0034599
• RNA processing
  http://purl.obolibrary.org/obo/GO_0006396
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• exonuclease activity
  http://purl.obolibrary.org/obo/GO_0004527
• regulation of cellular senescence
  http://purl.obolibrary.org/obo/GO_2000772
• polyribonucleotide nucleotidyltransferase activity
  http://purl.obolibrary.org/obo/GO_0004654
• poly(U) RNA binding
  http://purl.obolibrary.org/obo/GO_0008266
• RNA polyadenylation
  http://purl.obolibrary.org/obo/GO_0043631
• mRNA catabolic process
  http://purl.obolibrary.org/obo/GO_0006402
• protein homooligomerization
  http://purl.obolibrary.org/obo/GO_0051260
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• mRNA processing
  http://purl.obolibrary.org/obo/GO_0006397
• mitochondrial degradosome
  http://purl.obolibrary.org/obo/GO_0045025
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• RNA catabolic process
  http://purl.obolibrary.org/obo/GO_0006401
• nuclear polyadenylation-dependent mRNA catabolic process
  http://purl.obolibrary.org/obo/GO_0071042
• protein homotrimerization
  http://purl.obolibrary.org/obo/GO_0070207
• RNA import into mitochondrion
  http://purl.obolibrary.org/obo/GO_0035927
• regulation of cellular respiration
  http://purl.obolibrary.org/obo/GO_0043457
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• mitochondrial intermembrane space
  http://purl.obolibrary.org/obo/GO_0005758
• rRNA import into mitochondrion
  http://purl.obolibrary.org/obo/GO_0035928
• mitotic cell cycle arrest
  http://purl.obolibrary.org/obo/GO_0071850
• positive regulation of miRNA catabolic process
  http://purl.obolibrary.org/obo/GO_2000627
• positive regulation of mRNA catabolic process
  http://purl.obolibrary.org/obo/GO_0061014
• nucleotidyltransferase activity
  http://purl.obolibrary.org/obo/GO_0016779
• nuclease activity
  http://purl.obolibrary.org/obo/GO_0004518

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00240
• http://www.genome.jp/dbget-bin/www_bget?map03018
• http://www.genome.jp/dbget-bin/www_bget?map00230

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• RNA degradation
• Pyrimidine metabolism
• Purine metabolism