CD42200

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD42200

CD42200

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Galc

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• galactosylceramidase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• galactocerebroside beta-galactosidase
• galactosylceramide beta-galactosidase
• galactosylceramidase
• GALCERase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• A930008M05Rik
• 2310068B06Rik
• galactocerebrosidase
• Gacy
• twi
• AW212969
• AW413532
• twitcher

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/14420

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• galactosylceramidase
  http://metadb.riken.jp/db/mgi_rdf/MGI:95636

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008079

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000021003

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.5120

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=606890

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Ilaria. Visigalli, et.al., The galactocerebrosidase enzyme contributes to the maintenance of a functional hematopoietic stem cell niche., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20511539
• B. Ruggeri, et.al., Alterations of the p53 tumor suppressor gene during mouse skin tumor progression., Cancer research, 1991, 51
  http://rdf.ncbi.nlm.nih.gov/pubmed/1742735
• W. Huppes, et.al., Detection of migrated allogeneic oligodendrocytes throughout the central nervous system of the galactocerebrosidase-deficient twitcher mouse., Journal of neurocytology, 1992, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/1348528
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Y. Higashi, et.al., The twitcher mouse: immunocytochemical study of Ia expression in macrophages., Journal of neuropathology and experimental neurology, 1992, 51
  http://rdf.ncbi.nlm.nih.gov/pubmed/1740674
• http://rdf.ncbi.nlm.nih.gov/pubmed/20441793
• S M. LeVine, et.al., Morphological features of degenerating oligodendrocytes in twitcher mice., Brain research, 1992, 587
  http://rdf.ncbi.nlm.nih.gov/pubmed/1525668
• Giovanna. Pannuzzo, et.al., A galactose-free diet enriched in soy isoflavones and antioxidants results in delayed onset of symptoms of Krabbe disease in twitcher mice., Molecular genetics and metabolism, 2010, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/20418135
• Xing-Li. Meng, et.al., Induced pluripotent stem cells derived from mouse models of lysosomal storage disorders., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20385825
• A. Komiyama, et.al., Progressive impairment of Schwann cell proliferation in vitro in murine globoid cell leukodystrophy (twitcher)., Brain research, 1992, 598
  http://rdf.ncbi.nlm.nih.gov/pubmed/1486471

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• galactosylceramide catabolic process
  http://purl.obolibrary.org/obo/GO_0006683
• galactosylceramidase activity
  http://purl.obolibrary.org/obo/GO_0004336
• cation binding
  http://purl.obolibrary.org/obo/GO_0043169
• catalytic activity
  http://purl.obolibrary.org/obo/GO_0003824
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• hydrolase activity, acting on glycosyl bonds
  http://purl.obolibrary.org/obo/GO_0016798
• carbohydrate metabolic process
  http://purl.obolibrary.org/obo/GO_0005975
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• lysosome
  http://purl.obolibrary.org/obo/GO_0005764

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map01100
• http://www.genome.jp/dbget-bin/www_bget?map04142
• http://www.genome.jp/dbget-bin/www_bget?map00600

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Sphingolipid metabolism
• Lysosome
• Metabolic pathways