CD43825

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD43825

CD43825

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Diap1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• diaphanous homolog 1 (Drosophila)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• mDIA1
• protein diaphanous homolog 1
• diaphanous-related formin-1
• diaphanous homolog 1 (Drosophila)

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• p140mDia
• mKIAA4062
• Diaph1
• D18Wsu154e
• Drf1
• Dia1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/13367

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• diaphanous related formin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1194490

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007858

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000024456

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.195916

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602121

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Hiroaki. Mizuno, et.al., Rotational movement of the formin mDia1 along the double helical strand of an actin filament., Science (New York, N.Y.), 2011, 331
  http://rdf.ncbi.nlm.nih.gov/pubmed/21148346
• Hua. Sun, et.al., Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2)., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21278336
• F. Dangond, et.al., Cloning and expression of a murine histone deacetylase 3 (mHdac3) cDNA and mapping to a region of conserved synteny between murine chromosome 18 and human chromosome 5., Molecular cell biology research communications : MCBRC, 1999, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/10542131
• T. Fujiwara, et.al., Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2., Biochemical and biophysical research communications, 2000, 271
  http://rdf.ncbi.nlm.nih.gov/pubmed/10814512
• T. Tominaga, et.al., Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling., Molecular cell, 2000, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/10678165
• M S. Ko, et.al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome., Human molecular genetics, 1998, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/9811942
• Masahiro. Tanji, et.al., mDia1 targets v-Src to the cell periphery and facilitates cell transformation, tumorigenesis, and invasion., Molecular and cellular biology, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20679479
• Takanori. Otomo, et.al., Crystal structure of the Formin mDia1 in autoinhibited conformation., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/20927343
• Hideaki. Tanizaki, et.al., Rho-mDia1 pathway is required for adhesion, migration, and T-cell stimulation in dendritic cells., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20881208
• N. Watanabe, et.al., p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin., The EMBO journal, 1997, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/9214622

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cell projection
  http://purl.obolibrary.org/obo/GO_0042995
• ruffle membrane
  http://purl.obolibrary.org/obo/GO_0032587
• regulation of microtubule-based process
  http://purl.obolibrary.org/obo/GO_0032886
• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856
• actin binding
  http://purl.obolibrary.org/obo/GO_0003779
• Rho GTPase binding
  http://purl.obolibrary.org/obo/GO_0017048
• positive regulation of cell migration
  http://purl.obolibrary.org/obo/GO_0030335
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0007010
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• profilin binding
  http://purl.obolibrary.org/obo/GO_0005522
• neuron projection
  http://purl.obolibrary.org/obo/GO_0043005
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• actin cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0030036
• sensory perception of sound
  http://purl.obolibrary.org/obo/GO_0007605
• cellular component organization
  http://purl.obolibrary.org/obo/GO_0016043
• binding
  http://purl.obolibrary.org/obo/GO_0005488
• actin filament polymerization
  http://purl.obolibrary.org/obo/GO_0030041
• neuron projection development
  http://purl.obolibrary.org/obo/GO_0031175
• regulation of cell shape
  http://purl.obolibrary.org/obo/GO_0008360
• membrane
  http://purl.obolibrary.org/obo/GO_0016020

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04810
• http://www.genome.jp/dbget-bin/www_bget?map04510

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Regulation of actin cytoskeleton
• Focal adhesion