CD44776

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD44776

CD44776

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Nr5a2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• nuclear receptor subfamily 5, group A, member 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• liver receptor homolog 1
• nuclear receptor subfamily 5 group A member 2
• fetoprotein transcription factor
• nuclear receptor subfamily 5, group A, member 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AU020803
• Ftf
• D1Ertd308e
• LRH-1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/26424

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• nuclear receptor subfamily 5, group A, member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346834

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_030676
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001159769

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000026398

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.16794

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=604453

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Ge. Guo, et.al., A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency., Development (Cambridge, England), 2010, 137
  http://rdf.ncbi.nlm.nih.gov/pubmed/20823062
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Victoria R. Kelly, et.al., Dax1 up-regulates Oct4 expression in mouse embryonic stem cells via LRH-1 and SRA., Molecular endocrinology (Baltimore, Md.), 2010, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/20943815
• http://rdf.ncbi.nlm.nih.gov/pubmed/20932939
• Taiga. Suzuki, et.al., LXXLL-related motifs in Dax-1 have target specificity for the orphan nuclear receptors Ad4BP/SF-1 and LRH-1., Molecular and cellular biology, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/12482977
• L. Galarneau, et.al., The alpha1-fetoprotein locus is activated by a nuclear receptor of the Drosophila FTZ-F1 family., Molecular and cellular biology, 1996, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/8668203
• J F. Pare, et.al., The mouse fetoprotein transcription factor (FTF) gene promoter is regulated by three GATA elements with tandem E box and Nkx motifs, and FTF in turn activates the Hnf3beta, Hnf4alpha, and Hnf1alpha gene promoters., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11145965
• F M. Rausa, et.al., The nuclear receptor fetoprotein transcription factor is coexpressed with its target gene HNF-3beta in the developing murine liver, intestine and pancreas., Mechanisms of development, 1999, 89
  http://rdf.ncbi.nlm.nih.gov/pubmed/10559496
• Victoria R. Kelly, et.al., LRH-1 and Nanog regulate Dax1 transcription in mouse embryonic stem cells., Molecular and cellular endocrinology, 2011, 332
  http://rdf.ncbi.nlm.nih.gov/pubmed/20937355
• Frank. Chen, et.al., Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter., The Journal of biological chemistry, 2003, 278
  http://rdf.ncbi.nlm.nih.gov/pubmed/12456679

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• intracellular receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0030522
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• steroid hormone mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0043401
• lipid binding
  http://purl.obolibrary.org/obo/GO_0006630
• transcription regulatory region DNA binding
  http://purl.obolibrary.org/obo/GO_0044212
• lipid binding
  http://purl.obolibrary.org/obo/GO_0008289
• steroid hormone receptor activity
  http://purl.obolibrary.org/obo/GO_0003707
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• double-stranded DNA binding
  http://purl.obolibrary.org/obo/GO_0003690
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• bile acid metabolic process
  http://purl.obolibrary.org/obo/GO_0008206
• ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
  http://purl.obolibrary.org/obo/GO_0004879
• regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0042127
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• positive regulation of viral genome replication
  http://purl.obolibrary.org/obo/GO_0045070
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0043565
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• cholesterol homeostasis
  http://purl.obolibrary.org/obo/GO_0042632

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04950

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Maturity onset diabetes of the young