Q. Lu, et.al., Tyro-3 family receptors are essential regulators of mammalian spermatogenesis., Nature, 1999, 398

http://rdf.ncbi.nlm.nih.gov/pubmed/10227296

Q. Lu, et.al., Tyro-3 family receptors are essential regulators of mammalian spermatogenesis., Nature, 1999, 398

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD05913
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05913

allele

http://purl.org/net/cito/citesAsAuthority

• Tyro3<tm1Grl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387762
• Mertk<tm1Grl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387765
• Axl<tm1Grl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387750

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal spermatogenesis_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0001156I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• retinal rod cell degeneration_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0008451I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• retinal cone cell degeneration_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0008444I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• abnormal spleen morphology_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0000689I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• small testis_Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0001147I129S1Sv129X1SvJMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1Grl
• abnormal apoptosis_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0001648I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• abnormal prostate gland epithelium morphology_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0001168I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• reduced female fertility_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0001923I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• abnormal spermatogenesis_Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0001156I129S1Sv129X1SvJMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1Grl
• abnormal seminiferous tubule morphology_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0002216I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• abnormal blood vessel morphology_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0001614I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• liver degeneration_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0003103I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• azoospermia_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0005159I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• abnormal spermatogenesis_Axl<tm1Grl>/Axl<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0001156I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlTyro3tm1GrlTyro3tm1GrlAxltm1GrlTyro3tm1Grl
• oligozoospermia_Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0002687I129S1Sv129X1SvJMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1Grl
• abnormal hippocampus morphology_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0000807I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• small testis_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0001147I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• male infertility_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0001925I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• small testis_Axl<tm1Grl>/Axl<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0001147I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlTyro3tm1GrlTyro3tm1GrlAxltm1GrlTyro3tm1Grl
• blindness_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0002001I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• abnormal cerebellum morphology_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0000849I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• abnormal cerebral cortex morphology_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0000788I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• abnormal seizure response to inducing agent_Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0009357I129S1Sv129X1SvJTyro3tm1GrlTyro3tm1GrlTyro3tm1Grl
• enlarged spleen_Mertk<tm1Grl>/Mertk<tm1Grl>
  http://metadb.riken.jp/0000691I129P2OlaHsdMertktm1GrlMertktm1GrlMertktm1Grl
• increased granulosa cell apoptosis_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0013508I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl
• enlarged spleen_Axl<tm1Grl>/Axl<tm1Grl>,Mertk<tm1Grl>/Mertk<tm1Grl>,Tyro3<tm1Grl>/Tyro3<tm1Grl>
  http://metadb.riken.jp/0000691I129S1Sv129X1SvJC57BL6JAxltm1GrlAxltm1GrlMertktm1GrlMertktm1GrlTyro3tm1GrlTyro3tm1GrlMertktm1GrlTyro3tm1GrlAxltm1Grl