I. Satokata, et.al., Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation., Nature genetics, 2000, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/10742104

I. Satokata, et.al., Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation., Nature genetics, 2000, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD15959
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15959

allele

http://purl.org/net/cito/citesAsAuthority

• Msx2<tm1Rilm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926381

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal trabecular bone morphology_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000130EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• cerebellum vermis hypoplasia_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000866EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• alopecia_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000414EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• premature hair loss_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0005114EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• long nails_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0012401EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• ameloblast degeneration_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000129EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• absent cerebellum vermis lobule VIII_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000870EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• small interparietal bone_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0004384EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• abnormal appendicular skeleton morphology_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0009250EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• decreased chondrocyte number_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000167EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• delaminated cerebellar granule layer_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000887EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• abnormal axial skeleton morphology_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0002114EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• short femur_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0003109EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• abnormal frontal bone morphology_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000107EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• abnormal mammary gland embryonic development_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0004135EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• degenerate molars_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000127EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• big ears_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000017EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• short tibia_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0002764EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• abnormal neurocranium morphology_Msx1<tm1Rilm>/Msx1<tm1Rilm>,Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000074I129S4SvJaeBALBcCD1Msx1tm1RilmMsx1tm1RilmMsx2tm1RilmMsx2tm1RilmMsx2tm1RilmMsx1tm1Rilm
• malocclusion_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000120EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• abnormal mammary gland development_Msx1<tm1Rilm>/Msx1<tm1Rilm>,Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000628I129S4SvJaeBALBcCD1Msx1tm1RilmMsx1tm1RilmMsx2tm1RilmMsx2tm1RilmMsx2tm1RilmMsx1tm1Rilm
• abnormal cerebellum anterior vermis morphology_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000867EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• chondrodystrophy_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0002657EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• small supraoccipital bone_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0004444EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• brittle teeth_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000126EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• abnormal bone ossification_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0008271EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• reduced enamel thickness_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0002577EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• arrest of tooth development_Msx1<tm1Rilm>/Msx1<tm1Rilm>,Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000118I129S4SvJaeBALBcCD1Msx1tm1RilmMsx1tm1RilmMsx2tm1RilmMsx2tm1RilmMsx2tm1RilmMsx1tm1Rilm
• absent cerebellum vermis lobule IX_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000871EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• abnormal long bone hypertrophic chondrocyte zone_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000165EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• abnormal neurocranium morphology_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000074EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• decreased hair follicle number_Msx1<tm1Rilm>/Msx1<tm1Rilm>,Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000379I129S4SvJaeBALBcCD1Msx1tm1RilmMsx1tm1RilmMsx2tm1RilmMsx2tm1RilmMsx2tm1RilmMsx1tm1Rilm
• decreased bone mineral density_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000063EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• decreased osteoclast cell number_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0004985EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• tonic seizures_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0002826EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• decreased compact bone thickness_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000135EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• delaminated Purkinje cell layer_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000884EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm
• abnormal cerebellum development_Msx2<tm1Rilm>/Msx2<tm1Rilm>
  http://metadb.riken.jp/0000854EI129S4SvJaeorI129S4SvJaeBALBcorI129S4SvJaeC57BL6JMsx2tm1RilmMsx2tm1RilmMsx2tm1Rilm