R S. Weiss, et.al., Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress., Genes & development, 2000, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/10921903

R S. Weiss, et.al., Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress., Genes & development, 2000, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD39228
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39228
• CD11908
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD11908

allele

http://purl.org/net/cito/citesAsAuthority

• Hus1<tm1Led>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927769

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal visceral yolk sac blood island morphology_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0011204EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• incomplete rostral neuropore closure_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0000928EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• increased cellular sensitivity to ultraviolet irradiation_Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0008410I129S6SvEvTacCdkn1atm1LedCdkn1atm1LedHus1tm1LedHus1tm1LedCdkn1atm1LedHus1tm1Led
• increased cellular sensitivity to hydroxyurea_Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0008409I129S6SvEvTacCdkn1atm1LedCdkn1atm1LedHus1tm1LedHus1tm1LedCdkn1atm1LedHus1tm1Led
• abnormal placenta labyrinth morphology_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0001716EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• abnormal vitelline vasculature morphology_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0003229EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• decreased embryo size_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0001698EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• chromosome breakage_Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0004028I129S6SvEvTacCdkn1atm1LedCdkn1atm1LedHus1tm1LedHus1tm1LedCdkn1atm1LedHus1tm1Led
• abnormal somite development_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0001688EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• abnormal somite shape_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0001691EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• failure of initiation of embryo turning_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0004180EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• abnormal allantois morphology_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0001726EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• increased embryonic tissue cell apoptosis_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0013504EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• failure of chorioallantoic fusion_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0009657EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• absent fibroblast proliferation_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0011705EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• embryonic growth retardation_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0003984EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• absent limb buds_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0004573EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• kinked neural tube_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0003400EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• abnormal embryonic hematopoiesis_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0003396EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• embryonic lethality during organogenesis, complete penetrance_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0011098EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• chromosome breakage_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0004028EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• abnormal visceral yolk sac morphology_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0001718EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led
• abnormal placental labyrinth vasculature morphology_Hus1<tm1Led>/Hus1<tm1Led>
  http://metadb.riken.jp/0008803EI129S6SvEvTacorI129S6SvEvTacBlackSwissHus1tm1LedHus1tm1LedHus1tm1Led