Inessa. Grinberg, et.al., Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation., Nature genetics, 2004, 36

http://rdf.ncbi.nlm.nih.gov/pubmed/15338008

Inessa. Grinberg, et.al., Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation., Nature genetics, 2004, 36

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD05533
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05533

allele

http://purl.org/net/cito/citesAsAuthority

• Zic1/Zic4<tm1Kjmi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3510680
• Zic4<tm2Kjmi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3510678
• Zic1/Zic4<tm1Kjmi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3510681

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body weight_Zic1/Zic4<tm1Kjmi>/Zic4<+>
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic4Zic1Zic4tm1KjmiZic4
• abnormal cerebellum vermis morphology_Zic1/Zic4<tm1Kjmi>/Zic1<+>
  http://metadb.riken.jp/0000864I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic1Zic1Zic4tm1KjmiZic1
• abnormal cerebellar foliation_Zic1<tm1Jaru>/Zic1<+>
  http://metadb.riken.jp/0000857I129S4SvJaeC57BL6JC3HHeNZic1tm1JaruZic1Zic1Zic1tm1Jaru
• postnatal lethality, incomplete penetrance_Zic1/Zic4<tm1Kjmi>/Zic1<+>
  http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic1Zic1Zic4tm1KjmiZic1
• decreased body weight_Zic1/Zic4<tm1Kjmi>/Zic1<+>
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic1Zic1Zic4tm1KjmiZic1
• cerebellum hypoplasia_Zic4<tm2Kjmi>/Zic4<+>
  http://metadb.riken.jp/0000851I129P2OlaHsdC57BL6JZic4tm2KjmiZic4Zic4Zic4tm2Kjmi
• impaired righting response_Zic1/Zic4<tm1Kjmi>/Zic1<+>
  http://metadb.riken.jp/0001523I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic1Zic1Zic4tm1KjmiZic1
• abnormal cerebellum vermis morphology_Zic1<tm1Jaru>/Zic1<+>
  http://metadb.riken.jp/0000864I129S4SvJaeC57BL6JC3HHeNZic1tm1JaruZic1Zic1Zic1tm1Jaru
• ataxia_Zic1/Zic4<tm1Kjmi>/Zic1<+>
  http://metadb.riken.jp/0001393I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic1Zic1Zic4tm1KjmiZic1
• cerebellum vermis hypoplasia_Zic1/Zic4<tm1Kjmi>/Zic4<+>
  http://metadb.riken.jp/0000866I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic4Zic1Zic4tm1KjmiZic4
• ataxia_Zic1/Zic4<tm1Kjmi>/Zic4<+>
  http://metadb.riken.jp/0001393I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic4Zic1Zic4tm1KjmiZic4
• abnormal cerebellar foliation_Zic1/Zic4<tm1Kjmi>/Zic4<+>
  http://metadb.riken.jp/0000857I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic4Zic1Zic4tm1KjmiZic4
• cerebellum vermis hypoplasia_Zic1/Zic4<tm1Kjmi>/Zic1<+>
  http://metadb.riken.jp/0000866I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic1Zic1Zic4tm1KjmiZic1
• abnormal cerebellum vermis morphology_Zic1/Zic4<tm1Kjmi>/Zic4<+>
  http://metadb.riken.jp/0000864I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic4Zic1Zic4tm1KjmiZic4
• abnormal cerebellar foliation_Zic1/Zic4<tm1Kjmi>/Zic1<+>
  http://metadb.riken.jp/0000857I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic1Zic1Zic4tm1KjmiZic1
• impaired righting response_Zic1/Zic4<tm1Kjmi>/Zic4<+>
  http://metadb.riken.jp/0001523I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic4Zic1Zic4tm1KjmiZic4
• postnatal lethality, incomplete penetrance_Zic1/Zic4<tm1Kjmi>/Zic4<+>
  http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6JZic1Zic4tm1KjmiZic4Zic1Zic4tm1KjmiZic4
• abnormal cerebellar foliation_Zic4<tm2Kjmi>/Zic4<+>
  http://metadb.riken.jp/0000857I129P2OlaHsdC57BL6JZic4tm2KjmiZic4Zic4Zic4tm2Kjmi

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cerebellum vermis morphology in RBRC00702
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1001172
• abnormal cerebellum vermis morphology in RBRC00109
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1000299
• abnormal cerebellar foliation in RBRC00702
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010397
• abnormal cerebellar foliation in RBRC00109
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010352