Hua. Tian, et.al., Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand., Development (Cambridge, England), 2005, 132

http://rdf.ncbi.nlm.nih.gov/pubmed/15576405

Hua. Tian, et.al., Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand., Development (Cambridge, England), 2005, 132

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD28239
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28239

allele

http://purl.org/net/cito/citesAsAuthority

• Disp1<tm2.1Amc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3512545
• Shh<tm5Amc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3512786
• Disp1<tm2Amc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3512541

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal limb morphology_Disp1<icb>/Disp1<icb>
  http://metadb.riken.jp/0002109I129SvC57BL6JSWRDisp1icbDisp1icbDisp1icb
• absent floor plate_Disp1<tm2.1Amc>/Disp1<tm2.1Amc>,Shh<tm1Amc>/Shh<+>
  http://metadb.riken.jp/0000926I129SvC57BL6JSWRDisp1tm21AmcDisp1tm21AmcShhtm1AmcShhDisp1tm21AmcShhShhtm1Amc
• abnormal neuron differentiation_Disp1<tm2.1Amc>/Disp1<tm2.1Amc>,Shh<tm1Amc>/Shh<+>
  http://metadb.riken.jp/0009937I129SvC57BL6JSWRDisp1tm21AmcDisp1tm21AmcShhtm1AmcShhDisp1tm21AmcShhShhtm1Amc
• abnormal nasal pit morphology_Disp1<icb>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0006306I129SvC57BL6JSWRDisp1icbDisp1tm2AmcShhtm1EGFPcreCjtShhShhShhtm1EGFPcreCjtDisp1icbDisp1tm2Amc
• abnormal parietal bone morphology_Disp1<tm2.1Amc>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0000109I129SvC57BL6JSWRDisp1tm21AmcDisp1tm2AmcShhtm1EGFPcreCjtShhDisp1tm21AmcDisp1tm2AmcShhShhtm1EGFPcreCjt
• absent premaxilla_Disp1<icb>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0000090I129SvC57BL6JSWRDisp1icbDisp1tm2AmcShhtm1EGFPcreCjtShhShhShhtm1EGFPcreCjtDisp1icbDisp1tm2Amc
• neonatal lethality_Disp1<icb>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0002058I129SvC57BL6JSWRDisp1icbDisp1tm2AmcShhtm1EGFPcreCjtShhShhShhtm1EGFPcreCjtDisp1icbDisp1tm2Amc
• abnormal neuron differentiation_Disp1<icb>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0009937I129SvC57BL6JSWRDisp1icbDisp1tm2AmcShhtm1EGFPcreCjtShhShhShhtm1EGFPcreCjtDisp1icbDisp1tm2Amc
• cyclopia_Shh<tm1(EGFP/cre)Cjt>/Shh<tm2Amc>
  http://metadb.riken.jp/0005163I129SvC57BL6JSWRShhtm1EGFPcreCjtShhtm2AmcShhtm2AmcShhtm1EGFPcreCjt
• abnormal head morphology_Disp1<tm2.1Amc>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0000432I129SvC57BL6JSWRDisp1tm21AmcDisp1tm2AmcShhtm1EGFPcreCjtShhDisp1tm21AmcDisp1tm2AmcShhShhtm1EGFPcreCjt
• absent parietal bone_Disp1<icb>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0004419I129SvC57BL6JSWRDisp1icbDisp1tm2AmcShhtm1EGFPcreCjtShhShhShhtm1EGFPcreCjtDisp1icbDisp1tm2Amc
• absent premaxilla_Disp1<tm2.1Amc>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0000090I129SvC57BL6JSWRDisp1tm21AmcDisp1tm2AmcShhtm1EGFPcreCjtShhDisp1tm21AmcDisp1tm2AmcShhShhtm1EGFPcreCjt
• abnormal frontonasal prominence morphology_Disp1<icb>/Disp1<icb>,Shh<tm1Amc>/Shh<tm5Amc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0009901I129SvC57BL6JSWRDisp1icbDisp1icbShhtm1AmcShhtm5AmcTgSox2cre1Amc0Disp1icbShhtm5AmcTgSox2cre1AmcShhtm1Amc
• abnormal heart development_Disp1<icb>/Disp1<icb>
  http://metadb.riken.jp/0000267I129SvC57BL6JSWRDisp1icbDisp1icbDisp1icb
• abnormal brain development_Disp1<icb>/Disp1<icb>
  http://metadb.riken.jp/0000913I129SvC57BL6JSWRDisp1icbDisp1icbDisp1icb
• abnormal facial morphology_Disp1<icb>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0003743I129SvC57BL6JSWRDisp1icbDisp1tm2AmcShhtm1EGFPcreCjtShhShhShhtm1EGFPcreCjtDisp1icbDisp1tm2Amc
• no abnormal phenotype detected_Disp1<tm2Amc>/Disp1<tm2Amc>
  http://metadb.riken.jp/0002169I129SvC57BL6JSWRDisp1tm2AmcDisp1tm2AmcDisp1tm2Amc
• abnormal somite development_Disp1<icb>/Disp1<icb>
  http://metadb.riken.jp/0001688I129SvC57BL6JSWRDisp1icbDisp1icbDisp1icb
• embryonic lethality, complete penetrance_Disp1<icb>/Disp1<icb>
  http://metadb.riken.jp/0011092I129SvC57BL6JSWRDisp1icbDisp1icbDisp1icb
• abnormal facial morphology_Disp1<icb>/Disp1<icb>
  http://metadb.riken.jp/0003743I129SvC57BL6JSWRDisp1icbDisp1icbDisp1icb
• neonatal lethality_Disp1<tm2.1Amc>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0002058I129SvC57BL6JSWRDisp1tm21AmcDisp1tm2AmcShhtm1EGFPcreCjtShhDisp1tm21AmcDisp1tm2AmcShhShhtm1EGFPcreCjt
• abnormal vascular development_Disp1<icb>/Disp1<icb>
  http://metadb.riken.jp/0000259I129SvC57BL6JSWRDisp1icbDisp1icbDisp1icb
• abnormal neural tube morphology_Shh<tm1(EGFP/cre)Cjt>/Shh<tm2Amc>
  http://metadb.riken.jp/0002151I129SvC57BL6JSWRShhtm1EGFPcreCjtShhtm2AmcShhtm2AmcShhtm1EGFPcreCjt
• perinatal lethality, complete penetrance_Disp1<icb>/Disp1<icb>,Shh<tm1Amc>/Shh<tm5Amc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011089I129SvC57BL6JSWRDisp1icbDisp1icbShhtm1AmcShhtm5AmcTgSox2cre1Amc0Disp1icbShhtm5AmcTgSox2cre1AmcShhtm1Amc
• absent floor plate_Disp1<icb>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0000926I129SvC57BL6JSWRDisp1icbDisp1tm2AmcShhtm1EGFPcreCjtShhShhShhtm1EGFPcreCjtDisp1icbDisp1tm2Amc
• abnormal neuron differentiation_Disp1<tm2.1Amc>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0009937I129SvC57BL6JSWRDisp1tm21AmcDisp1tm2AmcShhtm1EGFPcreCjtShhDisp1tm21AmcDisp1tm2AmcShhShhtm1EGFPcreCjt
• abnormal nasal pit morphology_Disp1<tm2.1Amc>/Disp1<tm2Amc>,Shh<tm1(EGFP/cre)Cjt>/Shh<+>
  http://metadb.riken.jp/0006306I129SvC57BL6JSWRDisp1tm21AmcDisp1tm2AmcShhtm1EGFPcreCjtShhDisp1tm21AmcDisp1tm2AmcShhShhtm1EGFPcreCjt