Pascal. Descargues, et.al., Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity., Nature genetics, 2005, 37

http://rdf.ncbi.nlm.nih.gov/pubmed/15619623

Pascal. Descargues, et.al., Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity., Nature genetics, 2005, 37

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD24891
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD24891

allele

http://purl.org/net/cito/citesAsAuthority

• Spink5<tm1Hov>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3573756

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal epidermal layer morphology_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0001216I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• hyperkeratosis_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0001242I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• abnormal vibrissa morphology_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0002098I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• abnormal hair shaft morphology_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0003809I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• impaired skin barrier function_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0002796I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• abnormal vibrissa follicle morphology_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0010234I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• sparse vibrissae_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0001283I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• reddish skin_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0001190I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• skin lesions_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0001212I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• abnormal epidermis stratum corneum morphology_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0001240I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• epidermal desquamation_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0001230I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• scaly skin_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0001192I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• decreased skin tensile strength_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0003089I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• abnormal hair follicle morphology_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0000377I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• neonatal lethality, complete penetrance_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0011087I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• acanthosis_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0001874I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• abnormal epidermis stratum granulosum morphology_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0001239I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov
• parakeratosis_Spink5<tm1Hov>/Spink5<tm1Hov>
  http://metadb.riken.jp/0003427I129P2OlaHsdFVBSpink5tm1HovSpink5tm1HovSpink5tm1Hov